Active Ingredient History

  • Now
Difluprednate is a corticosteroid used as an anti-inflammatory steroidal drug used primarily in ocular surgery. It is thought to act by the induction of phospholipase A2 inhibitory proteins (lipocortins). It is postulated that these proteins control the biosynthesis of potent mediators of infammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A2. It is marketed by Alcon under the tradename Durezol.   NCATS

  • SMILES: CCCC(=O)O[C@@]1(CC[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C(=O)COC(C)=O
  • Mol. Mass: 508.5515
  • ALogP: 3.52
  • ChEMBL Molecule:
More Chemistry
  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Prescription Only
  • Delivery Methods: Topical
  • Pro Drug: Yes

Drug Pricing (per unit)

United States

$26.9500 - $39.7951
More Pricing Detail

Note: This drug pricing data is preliminary, incomplete, and may contain errors.

6 alpha-9-difluoroprednisolone 21-acetate 17-butyrate | c.m.9155 | dfba | difluoroprednisolone butyrate acetate | difluprednate | durezol | epitopic | w-6309


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