Active Ingredient History
Pneumococcal polysaccharide vaccine (PPSV)—known as Pneumovax 23 (PPV-23)—is the first pneumococcal vaccine derived from a capsular polysaccharide. Its development is an important landmark in medical history. The polysaccharide antigens were used to induce type-specific antibodies that enhanced opsonization, phagocytosis, and killing of Streptococcus pneumoniae (pneumococcal) bacteria by phagocytic immune cells. The pneumococcal polysaccharide vaccine is widely used in high-risk adults. As a result, there have been important reductions in the incidence, morbidity, and mortality from invasive pneumococcal disease. Wikipedia
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
Aged (Phase 4)
Aging (Early Phase 1)
Anemia, Sickle Cell (Phase 2)
Arthritis, Juvenile (Phase 3)
Arthritis, Rheumatoid (Phase 4)
Asthma (Phase 4)
Axial Spondyloarthritis (Phase 4)
Bone Marrow Transplantation (Phase 4)
Breast Neoplasms (Phase 1)
Colorectal Neoplasms (Phase 1)
Common Variable Immunodeficiency (Phase 2)
COVID-19 (Phase 4)
Crohn Disease (Phase 4)
Deficiency Diseases (Phase 4)
Diabetes Mellitus, Type 1 (Phase 4)
Diphtheria (Phase 2)
Haemophilus influenzae type b (Phase 2)
Healthy Volunteers (Phase 3)
Hematologic Diseases (Phase 2)
Hepatitis A (Phase 2)
Hepatitis B (Phase 2)
Herpes Zoster (Phase 3)
Herpes Zoster Vaccine (Phase 3)
HIV (Phase 4)
HIV-Associated Lipodystrophy Syndrome (Phase 1)
HIV Infections (Phase 3)
Immunization (Phase 2)
Infections (Phase 1/Phase 2)
Inflammatory Bowel Diseases (Phase 2)
Influenza, Human (Phase 4)
Kidney Transplantation (Phase 4)
Leukemia, Lymphocytic, Chronic, B-Cell (Phase 4)
Liver Transplantation (Phase 4)
Lung Diseases (Phase 4)
Lupus Erythematosus, Systemic (Phase 4)
Lymphoma, Large B-Cell, Diffuse (Phase 3)
Meningitis (Phase 2)
Meningococcal Infections (Phase 4)
Multiple Myeloma (Phase 2)
Multiple Sclerosis (Phase 3)
Multiple Sclerosis, Relapsing-Remitting (Phase 3)
Pertussis Vaccine (Phase 2)
Pneumococcal Infections (Phase 4)
Pneumococcal Vaccines (Phase 3)
Pneumonia (Phase 4)
Pneumonia, Bacterial (Phase 1)
Pneumonia, Pneumococcal (Phase 4)
Pneumonia, Staphylococcal (Phase 4)
Poliomyelitis (Phase 2)
Psoriasis (Phase 4)
Pulmonary Disease, Chronic Obstructive (Phase 4)
Sjogren's Syndrome (Phase 4)
Splenectomy (Phase 2)
Streptococcal Infections (Phase 3)
Streptococcus pneumoniae (Phase 3)
Systemic Vasculitis (Phase 4)
Tetanus (Phase 2)
Transplants (Phase 4)
Urinary Bladder Neoplasms (Phase 1)
Vaccination (Phase 4)
| Trial | Phase | Start Date | Organizations | Indications |
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