Active Ingredient History

  • Now
Clocortolone (used in form of pivalate prodrug) is a topical glucocorticoid that was approved by FDA for the treatment of corticosteroid-responsive skin disorders. The drug exerts its anti-inflammatory action by binding to glucocorticoid receptor which results in regulation of the expression of proinflammatory cytokines and further antiproliferative, immunosuppressive, and initial vasoconstrictive effects.   NCATS

  • SMILES: C[C@@H]1C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]2(C)[C@H]1C(=O)CO
  • Mol. Mass: 410.907
  • ALogP: 4.6
  • ChEMBL Molecule:
More Chemistry
  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Prescription Only
  • Delivery Methods: Topical
  • Pro Drug: No

Drug Pricing (per unit)

United States

$3.0257 - $511.2800
More Pricing Detail

Note: This drug pricing data is preliminary, incomplete, and may contain errors.

9 alpha-chloro-6 alpha-fluoro-11 beta,21- dihydroxy-16 alpha-methylpregna-1,4-diene-3,20- dione 21-pivalate | 9-chloro-6alpha-fluoro-11beta,21-dihydroxy-16alpha-methyl-1,4-pregnadien-3,20-dione | 9-chloro-6 alpha-fluoro-11 beta,21-dihydroxy- 16 alpha-methylpregnadiene-3,20-dione 21-acetate | 9-chloro-6alpha-fluoro-16alpha-methyl-1,4-pregnadiene-11beta,21-diol-3,20-dione | cl 68 | clocortolon | clocortolona | clocortolone | clocortolone acetate | clocortolone pivalate | clocortolone trimethylacetate | clocortolonum | cloderm | purantix | sh-863


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