efavirenz (sustiva) Report issue

Small molecule Approved FDA Fast Track FDA Accelerated Approval FDA Priority Review FDA

Active Ingredient History

  • Now
Efavirenz (brand names Sustiva® and Stocrin®) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) and is used as part of highly active antiretroviral therapy (HAART) for the treatment of a human immunodeficiency virus (HIV) type 1. For HIV infection that has not previously been treated, efavirenz and lamivudine in combination with zidovudine or tenofovir is the preferred NNRTI-based regimen. Efavirenz is also used in combination with other antiretroviral agents as part of an expanded postexposure prophylaxis regimen to prevent HIV transmission for those exposed to materials associated with a high risk for HIV transmission.   NCATS

  • SMILES: FC(F)(F)[C@]1(OC(=O)NC2=CC=C(Cl)C=C12)C#CC3CC3
  • Mol. Mass: 315.675
  • ALogP: 4.07
  • ChEMBL Molecule:
More Chemistry
  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Prescription Only
  • Delivery Methods: Oral
  • Pro Drug: No

Drug Pricing (per unit)


$1.9003 - $5.7008

United States

$2.0403 - $32.8517
More Pricing Detail

Note: This drug pricing data is preliminary, incomplete, and may contain errors.

Combination drugs

( efavirenz (sustiva), tenofovir (viread), emtricitabine (emtriva) - other name: emtricitabine; tenofovir    disoproxil fumarate; efavirenz )
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( efavirenz (sustiva), tenofovir (viread), lamivudine (epivir) - other names: efavirenz, lamivudine,and tenofovir disoproxil fumarate, symfi )
6-chloro-4-(2-cyclopropyl-1-ethynyl)-4-trifluoromethyl-(4s)-1,4-dihydro-2h-benzo[d][1,3]oxazin-2-one | (-)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-2h-3,1-benzoxazin-2-one | bristol-myers squibb brand of efavirenz | dmp 266 | dmp-266 | du pont brand of efavirenz | efavirenz | (-)-efavirenz | éfavirenz | efavirenza | efavirenz / emtricitabine / tenofovir disoproxil fumarate | efavirenz / emtricitabine / tenofovir disoproxil maleate | efavirenz / emtricitabine / tenofovir disoproxil, phosphate | efavirenz / emtricitabine / tenofovir disoproxil succinate | efavirenz, (r)-isomer | efavirenz, (s)-isomer | efavirenzum | efavirenzy | l 743726 | l 743,726 | l-743726 | l-743,726 | merck sharp & dohme brand of efavirenz | nano-efavirenz | nano-lopinavir | (s)-6-chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2h-3,1-benzoxazin-2-one | (s)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-2h-3,1-benzoxazin-2-one | (s)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one | stocrin | sustiva | sustiva 600 | united drug brand of efavirenz


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