Active Ingredient History

  • Now
Chlorambucil is a bifunctional 12 alkylating agent of the nitrogen mustard type that has been found active against selected human 13 neoplastic diseases. Chlorambucil alkylates and cross-links DNA during all phases of the cell cycle, inducing DNA damage via three different methods of covalent adduct generation with double-helical DNA. Bone marrow suppression (anemia, neutropenia, thrombocytopenia) is the most commonly occurring side effect of chlorambucil. There are no known drug/drug interactions with chlorambucil.   NCATS

  • Mol. Mass: 304.212
  • ALogP: 3.38
  • ChEMBL Molecule:
More Chemistry
  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: Yes
  • Availability: Prescription Only
  • Delivery Methods: Oral
  • Pro Drug: No

Drug Pricing (per unit)

More Pricing Detail

Note: This drug pricing data is preliminary, incomplete, and may contain errors.

4-[p-[bis(2-chloroethyl)amino]phenyl]butyric acid | 4-(p-bis(beta-chloroethyl)aminophenyl)butyric acid | 4-(p-bis(β-chloroethyl)aminophenyl)butyric acid | ambochlorin | amboclorin | chlorambucil | chloraminophen | chloraminophene | chlorbutin | chlorobutine | gamma-[p-di(2-chloroethyl)aminophenyl]butyric acid | leukeran | n,n-di-2-chloroethyl-gamma-p-aminophenylbutyric acid | n,n-di-2-chloroethyl-γ-p-aminophenylbutyric acid | phenylbutyric acid nitrogen mustard | γ-[p-di(2-chloroethyl)aminophenyl]butyric acid


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