Active Ingredient History

  • Now
Acitretin is all-Trans-9-(4-methoxy-2, 3, 6¬ trimethylphenyl)-three, 7-dimethyl-2, 4, 6, 8-nonatetraenoic acid. It is a metabolite of exterminate and is related to both retinoic acid and retinol (vitamin A). It is taken orally, and is typically used for psoriasis. The mechanism of action of is unknown. However it is believed to work by targeting specific receptors (retinoid receptors such as RXR and RAR) in the skin, which help normalize the growth cycle of skin cells. Studies on nuclear retinoic acid receptors have shown that acitretin activates all 3 receptor subtypes (RAR-alpha, -beta, and -gamma) without measurable receptor binding; this paradox remains unexplained.   NCATS

  • SMILES: COC1=CC(C)=C(\C=C\C(C)=C\C=C\C(C)=C\C(O)=O)C(C)=C1C
  • Mol. Mass: 326.4293
  • ALogP: 5.17
  • ChEMBL Molecule:
More Chemistry

Drug Pricing (per unit)

United States

$0.0003 - $53.3370


$0.7462 - $1.5176
More Pricing Detail

Note: This drug pricing data is preliminary, incomplete, and may contain errors.

acetretin | acitretin | acitretina | acitretine | acitretinoin | acitretinum | actiretin | (all-e)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid | all-trans-3,7-dimethyl-9-(4-methoxy-2,3,6-trimethylphenyl)-2,4,6,8-nonatetraenoic acid | etretin | isoacitretin | isoetretin | neotigason | ro-101670000 | soriatane


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