cetirizine (zyrtec) Report issue

Small molecule Approved FDA
AACT ChEMBL DrugBank Drug Central Drugs@FDA KEGG MeSH PubChem repoDB

Active Ingredient History

NOW
  • Now
Cetirizine, a human metabolite of hydroxyzine, is an antihistamine; its principal effects are mediated via selective inhibition of peripheral H1 receptors. It is indicated for the relief of nasal and non-nasal symptoms associated with seasonal or perennial allergic rhinitis, hay fever and chronic idiopathic urticaria. Commonly reported adverse reactions of cetirizine include headache, dry mouth and drowsiness or fatigue. Pharmacokinetic interaction studies with Cetirizine in adults were conducted with pseudoephedrine, antipyrine, ketoconazole, erythromycin and azithromycin. No interactions were observed.   NCATS

Chemistry

More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Over the Counter
  • Delivery Methods: Oral
  • Pro Drug: No

Drug Pricing (per unit)

United States

$0.0134 - $295.9800

Australia

$0.4386 - $0.5220
More Pricing Detail

Note: This drug pricing data is preliminary, incomplete, and may contain errors.

Combination drugs

( cetirizine (zyrtec), pseudoephedrine (Benylin) )

Alternative names

allacan | allertek | becoallergy | cetec | ceterizine | cetirizin | cetirizina | cetirizine | cetirizine di hcl | cetirizine dihydrochloride | cetirizine hcl | cetirizine hydrochloride | cetirizinum | cetirocol | p-071 | piriteze | pollenshield | ziralton | zirtek | zynor | zyrtec

Organizations (111)

Research & Development (69)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (50)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (35)

Approved Indications (3)


 

Rhinitis, Allergic, Perennial (approved 1995)

Rhinitis, Allergic, Seasonal

Urticaria

Experimental Indications - Clinical Trial Phases 1-4 (35)


 

Alopecia (Phase 4)

Altitude Sickness (Phase 4)

Asthma (Phase 4)

Breast Neoplasms (Phase 3)

Chronic Urticaria (Phase 2)

Conjunctivitis, Allergic (Phase 2)

COVID-19 (Phase 4)

Dermatitis (Phase 3)

Dermatitis, Atopic (Phase 3)

Diabetes Mellitus, Type 2 (Phase 4)

Diabetic Neuropathies (Phase 4)

Eczema (Phase 3)

Endometrial Neoplasms (Phase 3)

Esophageal Neoplasms (Phase 3)

Exercise (Phase 4)

Head and Neck Neoplasms (Phase 3)

Healthy Volunteers (Phase 1)

Hypersensitivity (Phase 4)

Lung Neoplasms (Phase 3)

Migraine Disorders (Phase 1)

Multiple Sclerosis (Phase 4)

Multiple Sclerosis, Relapsing-Remitting (Phase 4)

Neoplasms (Phase 2)

Neuralgia (Phase 4)

Neuromyelitis Optica (Phase 1/Phase 2)

Otitis Media with Effusion (Phase 4)

Ovarian Neoplasms (Phase 3)

Pemphigus (Phase 3)

Prostatitis (Early Phase 1)

Pruritus (Phase 4)

Rhinitis, Allergic (Phase 4)

Rhinitis, Allergic, Perennial (Phase 4)

Rhinitis, Allergic, Seasonal (Phase 4)

Urticaria (Phase 4)

Uterine Cervical Neoplasms (Phase 3)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 85
  • # of Trial Organizations: 69

Trials by Phase

Trial Phase Start Date Organizations Indications

Feedback

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