Active Ingredient History

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Cefazolin is a semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, cefazolin inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins. Cefazolin is used to treat bacterial infections of the skin, moderately severe bacterial infections involving the lung, bone, joint, stomach, blood, and urinary tract. It is clinically effective against infections caused by staphylococci and streptococci species of Gram positive bacteria. This drug also can be used for perioperative prophylaxis.   NCATS

  • SMILES: Cc1nnc(SCC2=C(N3[C@H](SC2)[C@H](NC(=O)Cn4cnnn4)C3=O)C(=O)O)s1
  • Mol. Mass: 454.52
  • ALogP: -0.64
  • ChEMBL Molecules:
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Drug Pricing (per unit)


$0.4884 - $2.1592

United States

$0.8944 - $10.5030
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Note: This drug pricing data is preliminary, incomplete, and may contain errors.

46083 | (6r,7r)-3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-8-oxo-7-[(1h-tetrazol-1-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid | ancef | cecefazolin | cefamezin | cefaprim | cefazil | cefazolin | cefazolina | cefazoline | cefazolin sodium | cefazolin sodium salt | cefazolinum | cephalozin | cephamezine | cephazolidin | cephazolin | cephazoline | cez | kefzol | sk&f-41558 | zolicef


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