canrenone (Contaren) Report issue

Small molecule Experimental
AACT ChEMBL DrugBank Drug Central KEGG MeSH PubChem

Active Ingredient History

NOW
  • Now
Canrenone, sold under the brand names Contaren, Luvion, Phanurane, and Spiroletan, is a steroidal antimineralocorticoid of the spirolactone group related to spironolactone which is used as a diuretic in Europe, including in Italy and Belgium. It is also an important active metabolite of spironolactone, and partially accounts for its therapeutic effects.   Wikipedia

Chemistry

  • SMILES: C[C@]12CCC(=O)C=C1C=C[C@@H]3[C@@H]2CC[C@@]4(C)[C@H]3CC[C@@]4(O)CCC(=O)O
  • InChIKey: PBKZPPIHUVSDNM-WNHSNXHDSA-N
  • Mol. Mass: 358.48
  • ALogP: 3.89
  • ChEMBL Molecules:
    canrenoate  
    canrenoate potassium  
    canrenone  
More Chemistry

Pharmacology

Alternative names

aldadiene | aldadiene kalium | aldadiene potassium | canrenoate | canrenoate potassium | canrenoic acid | canrenoic acid potassium | canrenoic acid potassium salt | canrenone | kanrenol | phanurane | potassium canrenoate | sc-14266 | sc-9376 | soldactone | spiroctan-m

Organizations (16)

Research & Development (16)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (7)

Approved Indications (1)


 

Hyperaldosteronism

Experimental Indications - Clinical Trial Phases 1-4 (6)


 

Atrial Fibrillation (Phase 4)

Brain Diseases (Phase 2)

COVID-19 (Phase 4)

Essential Hypertension (Phase 4)

Heart Failure (Phase 3)

ST Elevation Myocardial Infarction (Phase 3)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 8
  • # of Trial Organizations: 16

Trials by Phase

Trial Phase Start Date Organizations Indications

Feedback

Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).

Report issue