Active Ingredient History

  • Now
17α-Hydroxyprogesterone (17α-OHP), or hydroxyprogesterone (OHP), also known as 17α-hydroxypregn-4-ene-3, 20-dione is used under the brand name Gestageno, and has been marketed for clinical use in Argentina. It was indicated for female infertility, hypertrichosis, menstrual disorders, premature labour, threatened or recurrent miscarriage. It is used to properly regulate the menstrual cycle and treat unusual stopping of the menstrual periods (amenorrhea). To help a pregnancy occur during egg donor or infertility procedures in women who do not produce enough progesterone. To prevent estrogen from thickening the lining of the uterus (endometrial hyperplasia) in women around menopause who are being treated with estrogen for ovarian hormone therapy (OHT). To treat a condition called endometriosis, to help prevent endometrial hyperplasia, or to treat unusual and heavy bleeding of the uterus (dysfunctional uterine bleeding) by starting or stopping the menstrual cycle. 17α-OHP is an agonist of the progesterone receptor (PR) similarly to progesterone. In addition, it is an antagonist of the mineralocorticoid receptor (MR) as well as a partial agonist of the glucocorticoid receptor (GR), albeit with very low potency (EC50 >100-fold less relative to cortisol) at the latter site, also similarly to progesterone.   NCATS

More Chemistry
  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Prescription Only
  • Delivery Methods: Missing data
  • Pro Drug: No

Drug Pricing (per unit)

United States

$104.7700 - $752.6400
More Pricing Detail

Note: This drug pricing data is preliminary, incomplete, and may contain errors.

17-((1-oxohexyl)oxy)pregn-4-ene-3,20-dione | 17a-hydroxyprogesterone caproate | 17 alfa hydroxyprogesterone caproate | 17alpha-caproyloxypregn-4-ene-3,20-dione | 17alpha-hydroxyprogesterone | 17 alpha-hydroxy progesterone caproate | 17 alpha-hydroxyprogesterone caproate | 17-alpha-hydroxy-progesterone caproate | 17alpha hydroxy progesterone caproate | 17 alpha-hydroxyprogesterone capronate | 17alpha-hydroxyprogesterone hexanoate | 17 alpha-oxyprogesterone capronate | 17-hydroxyporgesterone caproate | 17-hydroxyprogesterone caproate | 17-hydroxyprogesterone capronate | 17α hydroxy progesterone caproate | alpha hydroxyprogesterone caproate | delalutin | dihydroxyprogesterone caproate | gestageno | hydroxyprogesterone | hydroxy-progesterone | hydroxyprogesterone caproate | hydroxyprogesterone hexanoate | makena | neolutin | oxiprogesterone caproate | oxyprogesterone caproate | primolut depot | progesterone caproate | prolutin depot | proluton depot


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