API | setanaxib

setanaxib Report issue

Small molecule Experimental

Active Ingredient History

NOW

Setanaxib is an experimental orally bioavailable dual inhibitor of NADPH oxidase isoforms NOX4 and NOX1. Setanaxib is a member of the pyrazolopyridine dione chemical series. The compound is the only specific NOX inhibitor that has entered into clinical trials. ^Wikipedia

Chemistry

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More Chemistry

Pharmacology

Mechanism of Action:
- Ecto-NOX disulfide-thiol exchanger 2 (Homo sapiens) ^UniProt
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Organizations (1)

Research & Development (1)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (0)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (2)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (2)

Liver (Phase 2/Phase 3)

Liver Cirrhosis, Biliary (Phase 2/Phase 3)

Overview

Highest Phase: Phase 3
# of Trials: 3
# of Trial Organizations: 1

Trials by Phase

Trial	Phase	Start Date	Organizations	Indications

Feedback

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