Active Ingredient History

  • Now
Cocarboxylase is the coenzyme form of Vitamin B1 present in many animal tissues. Thiamine pyrophosphate (cocarboxylase) is the active form of thiamine, and it serves as a cofactor for several enzymes involved primarily in carbohydrate catabolism. Pancreatic cells obtain thiamin from their surroundings and enzymatically convert it into thiamin pyrophosphate (TPP) in the cytoplasm; TPP is then taken up by mitochondria via a specific carrier the mitochondrial TPP transporter (MTPPT; product of the SLC25A19 gene).   NCATS

  • SMILES: [H+].CC1=C(CCOP([O-])(=O)OP(O)([O-])=O)SC=[N+]1CC2=CN=C(C)N=C2N
  • Mol. Mass: 424.306
  • ALogP: Missing data
  • ChEMBL Molecules: Missing data
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