aspartame Report issue

Small molecule Experimental
AACT ChEMBL DrugBank PubChem

Active Ingredient History

NOW
  • Now
Aspartame is an artificial non-saccharide sweetener 200 times sweeter than sucrose, and is commonly used as a sugar substitute in foods and beverages. It is a methyl ester of the aspartic acid/phenylalanine dipeptide with the trade names NutraSweet, Equal, and Canderel. First submitted for approval as a food ingredient in 1974, aspartame was approved by the United States Food and Drug Administration (FDA) in 1981.   Wikipedia

Chemistry

  • SMILES: COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CC(=O)O
  • InChIKey: IAOZJIPTCAWIRG-QWRGUYRKSA-N
  • Mol. Mass: 294.31
  • ALogP: -0.31
  • ChEMBL Molecule:
    aspartame  
More Chemistry

Pharmacology

Alternative names

1-methyl n-l-alpha-aspartyl-l-phenylalanate | 1-methyl n-l-alpha-aspartyl-l-phenylalanine | 1-methyl n-l-α-aspartyl-l-phenylalanate | 3-amino-n-(alpha-carboxyphenethyl)succinamic acid n-methyl ester | 3-amino-n-(alpha-methoxycarbonylphenethyl) succinamic acid | 3-amino-n-(α-carboxyphenethyl)succinamic acid n-methyl ester | 3-amino-n-(α-methoxycarbonylphenethyl) succinamic acid | apm | aspartam | aspartame | aspartamo | aspartamum | aspartylphenylalanine methyl ester | asp-phe-ome | e951 | l-aspartyl-l-phenylalanine methyl ester | sc-18862

Organizations (14)

Research & Development (14)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (2)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (2)


 

Colonoscopy (Phase 3)

Diabetes Mellitus, Type 2 (Phase 4)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 10
  • # of Trial Organizations: 14

Trials by Phase

Trial Phase Start Date Organizations Indications

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