API | tolerogenic dendritic cells

tolerogenic dendritic cells Report issue

Cell therapy Experimental

Active Ingredient History

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Tolerogenic dendritic cells are heterogenous pool of dendritic cells with immuno-suppressive properties, priming immune system into tolerogenic state against various antigens. These tolerogenic effects are mostly mediated through regulation of T cells such as inducing T cell anergy, T cell apoptosis and induction of Tregs. Tol-DCs also affect local micro-environment toward tolerogenic state by producing anti-inflammatory cytokines. ^Wikipedia

Chemistry

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Pharmacology

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Organizations (2)

Research & Development (2)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (0)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (8)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (8)

Arthritis (Phase 1)

Arthritis, Rheumatoid (Phase 1)

Autoimmune Diseases (Phase 1)

Connective Tissue Diseases (Phase 1)

Immune System Diseases (Phase 1)

Joint Diseases (Phase 1)

Musculoskeletal Diseases (Phase 1)

Rheumatic Diseases (Phase 1)

Overview

Highest Phase: Phase 2
# of Trials: 3
# of Trial Organizations: 2

Trials by Phase

Trial	Phase	Start Date	Organizations	Indications

Feedback

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