Hydroxytryptophan Report issue

Small molecule Experimental
AACT ChEMBL DrugBank Drug Central KEGG PubChem

Active Ingredient History

NOW
  • Now
5-Hydroxytryptophan (5-HTP), also known as oxitriptan, is a naturally occurring amino acid and chemical precursor as well as a metabolic intermediate in the biosynthesis of the neurotransmitter serotonin.   Wikipedia

Chemistry

  • SMILES: N[C@@H](Cc1c[nH]c2ccc(O)cc12)C(=O)O
  • InChIKey: LDCYZAJDBXYCGN-VIFPVBQESA-N
  • Mol. Mass: 220.23
  • ALogP: 0.83
  • ChEMBL Molecule:
    oxitriptan  
More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Missing data
  • Delivery Methods: Missing data
  • Pro Drug: No

Alternative names

5-hydroxy-l-tryptophan | 5 hydroxy-tryptophan | 5-hydroxytryptophan | 5-hydroxytryptophan l-form | cincofarm | hydroxy-5 l-tryptophane | l-5-hydroxytryptophan | levothym | levotinine | levotonine | oxitriptan | oxyfan | pretonine | tript-oh

Organizations (16)

Research & Development (16)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (11)

Approved Indications (1)


 

Depression

Experimental Indications - Clinical Trial Phases 1-4 (10)


 

Asthma (Phase 2)

Colitis, Ulcerative (Phase 2)

Crohn Disease (Phase 2)

Depressive Disorder, Major (Phase 4)

Fatigue (Phase 2)

Fragile X Syndrome (Phase 2)

Obesity (Phase 2)

Remission Induction (Phase 2)

Sleep Apnea, Obstructive (Phase 4)

Spinal Cord Injuries (Phase 2/Phase 3)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 17
  • # of Trial Organizations: 16

Trials by Phase

Trial Phase Start Date Organizations Indications

Feedback

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