threonate Report issue

Small molecule Experimental
AACT Drug Central MeSH PubChem

Active Ingredient History

NOW
  • Now
Magnesium L-Threonate (MgT) is the most appropriate Mg salt that strengthens the cholinergic system and improves brain-related functions. It is used to improve memory, assist with sleep, and to enhance overall cognitive function. Mg, an intracellular cofactor for many enzymes, is a modulator of the N-methyl-D-aspartate (NMDA) receptor that is involved in memory function and depression. Experiments on rodents have shown that oral magnesium-L-Threonate also prevents neuropathic pain induced by chemotherapy.   NCATS

Chemistry

  • SMILES: [Mg++].OC[C@H](O)[C@@H](O)C([O-])=O.OC[C@H](O)[C@@H](O)C([O-])=O
  • InChIKey: YVJOHOWNFPQSPP-BALCVSAKSA-L
  • Mol. Mass: 294.4958
  • ALogP: Missing data
  • ChEMBL Molecules: Missing data
More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: Missing data
  • Availability: Missing data
  • Delivery Methods: Missing data
  • Pro Drug: Missing data

Alternative names

2,3,4-trihydroxy-(threo)-butanoic acid | calcium l-threonate | calcium threonate | clarimem | l-tams compound | l-threonic acid magnesium salt | magnesium l-threonate | magnesium threonate | mmfs-01 | mmfs-202-302 | threonate | threonic acid | threonic acid, dl- | threonic acid, l- | threonic acid, (r*,r*)-isomer | threonic acid, (r-(r*,s*))-isomer

Organizations (9)

Research & Development (9)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (6)

Approved Indications (1)


 

Cognition

Experimental Indications - Clinical Trial Phases 1-4 (5)


 

Alzheimer Disease (Phase 2)

Attention Deficit Disorder with Hyperactivity (Phase 2)

Psychotic Disorders (Phase 4)

Schizophrenia (Phase 4)

X-Linked Combined Immunodeficiency Diseases (Phase 1/Phase 2)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 6
  • # of Trial Organizations: 9

Trials by Phase

Trial Phase Start Date Organizations Indications

Feedback

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