Active Ingredient History
Berberine is a quaternary ammonium salt from the protoberberine group of benzylisoquinoline alkaloids found in such plants as Berberis vulgaris (barberry), Berberis aristata, Mahonia aquifolium, Hydrastis canadensis (goldenseal), Xanthorhiza simplicissima (yellowroot), Phellodendron amurense, Coptis chinensis, Tinospora cordifolia, Argemone mexicana, and Eschscholzia californica. Berberine is usually found in the roots, rhizomes, stems, and bark. Wikipedia
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
Adenocarcinoma of Lung (Phase 2)
Atherosclerosis (Phase 4)
Atrophy (Phase 3)
Berberine (Phase 4)
Blood Pressure (Phase 4)
Colitis, Ulcerative (Phase 4)
Colorectal Neoplasms (Phase 3)
Coronary Artery Disease (Phase 4)
COVID-19 (Phase 4)
Cyclosteroids (Phase 2)
Diabetes Mellitus (Phase 4)
Diabetes Mellitus, Type 1 (Phase 4)
Diabetes Mellitus, Type 2 (Phase 3)
Drugs, Investigational (Phase 1)
Dyslipidemias (Phase 4)
Dyspepsia (Phase 4)
Endothelial Cells (Phase 4)
Esophageal and Gastric Varices (Phase 3)
Gastritis (Phase 4)
Glucose Intolerance (Phase 4)
Heart Disease Risk Factors (Phase 2/Phase 3)
Helicobacter pylori (Phase 4)
Hepatitis B (Phase 3)
Hepatitis C, Chronic (Phase 3)
HIV Infections (Phase 3)
Hypercholesterolemia (Phase 4)
Hyperglycemia (Phase 4)
Hyperlipidemias (Phase 4)
Hypertension (Phase 4)
Inflammation (Phase 4)
Lipodystrophy (Phase 3)
Lipoproteins (Phase 3)
Malabsorption Syndromes (Phase 1)
Malnutrition (Phase 3)
Metabolic Syndrome (Phase 4)
Metformin (Phase 4)
Mutation (Phase 2)
Non-alcoholic Fatty Liver Disease (Phase 4)
Oxidative Stress (Phase 3)
Peptic Ulcer (Phase 4)
Percutaneous Coronary Intervention (Phase 4)
Prediabetic State (Phase 4)
Renal Insufficiency, Chronic (Phase 4)
Schizophrenia (Phase 4)
Schizophrenia Spectrum and Other Psychotic Disorders (Phase 2/Phase 3)
Stomach Neoplasms (Phase 4)
Stomach Ulcer (Phase 4)
Therapeutics (Phase 4)
Triglycerides (Phase 3)
| Trial | Phase | Start Date | Organizations | Indications |
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