citicoline Report issue

Small molecule Experimental
AACT ChEMBL DrugBank Drug Central KEGG MeSH PubChem

Active Ingredient History

NOW
  • Now
Citicoline (INN), also known as cytidine diphosphate-choline (CDP-Choline) or cytidine 5'-diphosphocholine is an intermediate in the generation of phosphatidylcholine from choline, a common biochemical process in cell membranes. Citicoline is naturally occurring in the cells of human and animal tissue, in particular the organs.   Wikipedia

Chemistry

  • SMILES: C[N+](C)(C)CCOP(=O)(O)OP(=O)(O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=CC(=NC2=O)N
  • InChIKey: RZZPDXZPRHQOCG-OJAKKHQRSA-O
  • Mol. Mass: 489.34
  • ALogP: -1.6
  • ChEMBL Molecules:
    citicoline  
    citicoline sodium  
More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Missing data
  • Delivery Methods: Missing data
  • Pro Drug: No

Alternative names

cdp-cholin | cdp-choline | ceraxon | choline cytidine diphosphate | citicholine | citicoline | citicoline sodium | citidoline | corenalin | cyscholin | cytidine-5'-diphosphocholine | cytidine choline diphosphate | cytidine diphosphate choline | cytidine diphosphocholine | cytidine diphosphorylcholine | cytidoline | difosfocin | emicholine | ip-302-sodium

Organizations (51)

Research & Development (51)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (28)

Approved Indications (1)


 

Dietary Supplements

Experimental Indications - Clinical Trial Phases 1-4 (27)


 

Air Travel (Phase 2/Phase 3)

Alcoholism (Phase 4)

Bipolar Disorder (Phase 4)

Brain Injuries (Phase 2)

Brain Injuries, Traumatic (Phase 3)

Cerebral Infarction (Phase 4)

Cocaine-Related Disorders (Phase 4)

Cognition Disorders (Phase 2)

Delirium (Phase 4)

Diabetic Retinopathy (Phase 1)

Glaucoma (Phase 4)

Glaucoma, Open-Angle (Phase 1)

Hypoxia-Ischemia, Brain (Phase 3)

Infant, Premature (Phase 3)

Intensive Care Units (Phase 4)

Ischemic Stroke (Phase 3)

Mania (Phase 3)

Marijuana Abuse (Phase 2)

Methamphetamine (Phase 3)

Neonatology (Phase 3)

Neural Conduction (Phase 4)

Optic Nerve (Phase 4)

Optic Neuropathy, Ischemic (Phase 4)

Schizophrenia (Phase 2)

Stroke (Phase 3)

Substance-Related Disorders (Phase 2)

Visual Pathways (Phase 4)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 44
  • # of Trial Organizations: 51

Trials by Phase

Trial Phase Start Date Organizations Indications

Feedback

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