Active Ingredient History
Lactobacillus acidophilus is a rod-shaped, Gram-positive, homofermentative, anaerobic microbe first isolated from infant feces in the year 1900. The species is most commonly found in humans, specifically the gastrointestinal tract, oral cavity, and vagina, as well as various fermented foods such as fermented milk or yogurt. The species most readily grows at low pH levels, and has an optimum growth temperature of 37 °C. Certain strains of L. acidophilus show strong probiotic effects, and are commercially used in dairy production. The genome of L. acidophilus has been sequenced. Wikipedia
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
Abdominal Injuries (Phase 3)
Abdominal Pain (Phase 3)
Acute-On-Chronic Liver Failure (Phase 3)
Adenomatous Polyposis Coli (Phase 2)
Ascites (Phase 2)
Asthma (Phase 2/Phase 3)
Basal Ganglia Diseases (Phase 4)
Brain Diseases (Phase 4)
Candidiasis, Vulvovaginal (Phase 4)
Celiac Disease (Phase 4)
Central Nervous System Diseases (Phase 4)
Clostridium Infections (Phase 3)
Colic (Phase 2)
Colitis, Ulcerative (Phase 1)
Colonic Diseases, Functional (Phase 1/Phase 2)
Communicable Diseases (Phase 2)
Constipation (Phase 3)
Coronavirus Infections (Phase 2)
COVID-19 (Phase 2)
Crohn Disease (Phase 4)
Defecation (Phase 3)
Deglutition Disorders (Early Phase 1)
Diabetes Mellitus, Type 1 (Phase 4)
Diabetes Mellitus, Type 2 (Phase 4)
Diarrhea (Phase 3)
Digestive System Diseases (Phase 1/Phase 2)
Drug Resistance, Bacterial (Phase 2)
Dyspepsia (Phase 2/Phase 3)
Fatty Liver (Phase 1)
Hepatic Encephalopathy (Phase 3)
Hirschsprung Disease (Phase 2)
Hyperoxaluria (Phase 1/Phase 2)
Hypertension (Early Phase 1)
Inflammatory Bowel Diseases (Phase 3)
Insulin Resistance (Phase 1/Phase 2)
Interleukin-17 (Phase 2)
Intestinal Neoplasms (Phase 3)
Irritable Bowel Syndrome (Phase 4)
Klebsiella pneumoniae (Phase 1/Phase 2)
Live Birth (Phase 2)
Liver Cirrhosis (Phase 2/Phase 3)
Lower Urinary Tract Symptoms (Phase 2)
Menopause (Phase 2)
Metabolic Syndrome (Phase 4)
Movement Disorders (Phase 4)
Mucositis (Phase 3)
Neonatal Sepsis (Phase 3)
Neoplasms (Phase 3)
Nephrolithiasis (Phase 1/Phase 2)
Nervous System Diseases (Phase 4)
Neurodegenerative Diseases (Phase 4)
Non-alcoholic Fatty Liver Disease (Phase 1/Phase 2)
Osteoporosis (Phase 2)
Parkinson Disease (Phase 4)
Parkinsonian Disorders (Phase 4)
Peritonitis (Phase 3)
Pneumonia, Viral (Phase 2)
Polycystic Ovary Syndrome (Phase 3)
Pregnancy (Phase 4)
Probiotics (Phase 4)
Quality of Life (Phase 3)
Recurrence (Phase 4)
Respiratory Tract Infections (Phase 2)
Rhinitis, Allergic (Phase 4)
Rhinitis, Allergic, Seasonal (Phase 3)
Scleroderma, Systemic (Phase 4)
Sjogren's Syndrome (Phase 1/Phase 2)
Stomatitis (Phase 2)
Urinary Tract Infections (Phase 2)
Vaginosis, Bacterial (Phase 4)
| Trial | Phase | Start Date | Organizations | Indications |
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