Active Ingredient History
Botulinum toxin, or botulinum neurotoxin (BoNT), is a neurotoxic protein produced by the bacterium Clostridium botulinum and related species. It prevents the release of the neurotransmitter acetylcholine from axon endings at the neuromuscular junction, thus causing flaccid paralysis. The toxin causes the disease botulism. The toxin is also used commercially for medical and cosmetic purposes. Wikipedia
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
Arteries (Phase 2)
Beckwith-Wiedemann Syndrome (Phase 3)
Blepharitis (Phase 3)
Blepharospasm (Phase 4)
Botulinum Toxins (Phase 2)
Botulinum Toxins, Type A (Phase 4)
Bruxism (Phase 3)
Cerebral Palsy (Phase 3)
Chronic Exertional Compartment Syndrome (Phase 2)
Complex Regional Pain Syndromes (Early Phase 1)
Dermatology (Phase 2/Phase 3)
Dyspareunia (Phase 4)
Electromyography (Phase 3)
Epidermolysis Bullosa Simplex (Phase 2/Phase 3)
Erectile Dysfunction (Phase 2)
Fasciitis, Plantar (Phase 2)
Hemifacial Spasm (Phase 4)
Hyperhidrosis (Phase 3)
Jaw (Phase 2)
Muscle Spasticity (Phase 1/Phase 2)
Musculoskeletal Diseases (Phase 3)
Neoplasms (Phase 3)
Pain (Phase 3)
Pelvic Floor Disorders (Phase 3)
Pelvic Pain (Phase 4)
Pelvis (Phase 4)
Popliteal Artery Entrapment Syndrome (Phase 2)
Post-Traumatic Headache (Phase 4)
Raynaud Disease (Phase 4)
Rhytidoplasty (Phase 4)
Sclerosis (Phase 3)
Scoliosis (Phase 4)
Shoulder Pain (Phase 4)
Strabismus (Phase 3)
Stroke (Phase 3)
Talipes (Phase 4)
Urinary Bladder, Overactive (Phase 3)
Urinary Incontinence, Stress (Phase 3)
Urinary Incontinence, Urge (Phase 3)
| Trial | Phase | Start Date | Organizations | Indications |
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