Active Ingredient History
Botulinum toxin, or botulinum neurotoxin (BoNT), is a neurotoxic protein produced by the bacterium Clostridium botulinum and related species. It prevents the release of the neurotransmitter acetylcholine from axon endings at the neuromuscular junction, thus causing flaccid paralysis. The toxin causes the disease botulism. The toxin is also used commercially for medical and cosmetic purposes. Wikipedia
Drug Pricing (per unit)
Note: This drug pricing data is preliminary, incomplete, and may contain errors.
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
Blepharospasm (approved 1989)
Strabismus (approved 1989)
Acne Vulgaris (Phase 2)
Affect (Phase 1)
Aging (Phase 4)
Amputation Stumps (Phase 3)
Bariatric Surgery (Phase 4)
Blepharitis (Phase 4)
Blepharospasm (Early Phase 1)
Blood Transfusion (Phase 1)
Botulinum Toxins, Type A (Phase 4)
Bursitis (Early Phase 1)
Carotid Artery Diseases (Phase 1)
Catheterization (Phase 1)
Cerebral Palsy (Phase 3)
Chronic Exertional Compartment Syndrome (Phase 2/Phase 3)
Chronic Pain (Phase 4)
Cicatrix (Phase 3)
Cicatrix, Hypertrophic (Phase 4)
Cluster Headache (Phase 3)
Colostomy (Phase 2)
Contracture (Phase 3)
Cystitis, Interstitial (Phase 2)
Deglutition Disorders (Phase 2/Phase 3)
Depression (Phase 1)
Depressive Disorder, Major (Phase 1)
Depressive Disorder, Treatment-Resistant (Phase 1)
Dermatology (Phase 4)
Diabetes Mellitus (Phase 2)
Diabetes Mellitus, Type 2 (Phase 4)
Dystonia (Phase 3)
Dystonic Disorders (Phase 3)
Ectodermal Dysplasia 1, Anhidrotic (Phase 1)
Elbow (Phase 3)
Erectile Dysfunction (Phase 2/Phase 3)
Esophageal Achalasia (Phase 4)
Eye Diseases, Hereditary (Phase 4)
Fasciitis, Plantar (Phase 2)
General Surgery (Phase 2)
Gingival Diseases (Phase 3)
Gingival Overgrowth (Phase 1)
Groin (Phase 2)
Headache (Phase 3)
Headache Disorders, Secondary (Early Phase 1)
Healthy Volunteers (Phase 1)
Hemifacial Spasm (Phase 3)
Hemiplegia (Phase 4)
Hemorrhagic Stroke (Phase 1)
Hyperhidrosis (Phase 4)
Jaw (Phase 3)
Joint Diseases (Phase 2)
Knee (Phase 2)
Leg Injuries (Phase 4)
Magnetic Resonance Imaging (Phase 2)
Masseter Muscle (Phase 3)
Migraine Disorders (Phase 4)
Multiple Sclerosis (Phase 4)
Muscles (Phase 2/Phase 3)
Muscle Spasticity (Phase 4)
Myalgia (Phase 2)
Myofascial Pain Syndromes (Phase 3)
Neonatal Brachial Plexus Palsy (Phase 3)
Neoplasms (Phase 2)
Nerve Sheath Neoplasms (Phase 4)
Neuralgia (Phase 2)
Nocturia (Phase 4)
Obesity (Phase 4)
Pain (Phase 4)
Pain, Postoperative (Phase 2)
Pancreatic Neoplasms (Phase 2)
Paralysis (Early Phase 1)
Parkinson Disease (Phase 2/Phase 3)
Pelvic Floor (Early Phase 1)
Pelvic Floor Disorders (Early Phase 1)
Pelvic Organ Prolapse (Phase 4)
Penicillins (Phase 1)
Postoperative Nausea and Vomiting (Phase 4)
Raynaud Disease (Phase 4)
Rehabilitation (Phase 2)
Rhytidoplasty (Phase 4)
Scleroderma, Systemic (Early Phase 1)
Scoliosis (Phase 2)
Scrotum (Phase 4)
Sinusitis (Phase 3)
Sleep Bruxism (Phase 2)
Smiling (Phase 4)
Stroke (Phase 4)
Swallows (Phase 2/Phase 3)
Temporomandibular Joint Disorders (Phase 3)
Tendinopathy (Phase 2)
Tension-Type Headache (Phase 3)
Therapeutics (Phase 2)
Thoracic Surgery (Phase 3)
Thumb (Phase 4)
Torticollis (Phase 3)
Trigeminal Nerve Injuries (Phase 3)
Urinary Bladder, Neurogenic (Phase 4)
Urinary Bladder, Overactive (Phase 4)
Urinary Incontinence (Phase 4)
Urinary Incontinence, Stress (Early Phase 1)
Urinary Incontinence, Urge (Phase 4)
Urination Disorders (Phase 4)
Venous Thrombosis (Phase 1)
Vertebral Artery Dissection (Phase 1)
Vulvodynia (Phase 3)
Weight Loss (Phase 2/Phase 3)
| Trial | Phase | Start Date | Organizations | Indications |
|---|
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