Active Ingredient History

  • Now
Trifarotene is a novel first-in-class fourth-generation topical retinoid. It is a potent and selective RAR gamma-agonist. In multiple mouse models, trifarotene exhibited superior comedolytic, anti-inflammatory and depigmenting activity compared with other topical retinoids. In this 52-week study, trifarotene was safe, well-tolerated and effective in moderate facial and truncal acne. Trifarotene is in phase II clinical trial for the treatment of ichthyosis.   NCATS

  • SMILES: CC(C)(C)c1cc(ccc1N2CCCC2)c3cc(ccc3OCCO)c4ccc(cc4)C(=O)O
  • Mol. Mass: 459.59
  • ALogP: 5.99
  • ChEMBL Molecule:
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Drug Pricing (per unit)

United States

$9.4187 - $12.4198
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Note: This drug pricing data is preliminary, incomplete, and may contain errors.

cd5789 | trifarotene


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