lysine Report issue

Small molecule Experimental
AACT ChEMBL DrugBank Drug Central KEGG MeSH PubChem

Active Ingredient History

NOW
  • Now
Lysing is an essential basic amino-acid encoded by codone AAA and AAG, and used in the biosynthesis of proteins. The daily requirement for lysine is 38 mg/kg body weight. The most rich source of lysine is fish, beef, chicken. In a clinical study lysine supplements was found to be an effective for reduction of occurrence, severity and healing time for recurrent HSV infection, however Cochrane Review concluded that the evidence is insufficient. Lysine was investigated for improving anxiety, ameliorating angina prectoris. Lysine acetylsalicylate has been used to treat pain and to detoxify the body after heroin use. Lysine clonixinate has been used for its analgesic properties for the treatment of migraine headaches and other painful conditions. However, limited clinical trials exist for these conditions.   NCATS

Chemistry

More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Missing data
  • Delivery Methods: Missing data
  • Pro Drug: No

Alternative names

6-ammonio-l-norleucine | l-2,6-diaminocaproic acid | l-lys | l-lysin | l-lysine | l-(+)-lysine | lys | lysina | lysine | lysine acetate | lysine acid | lysine chloride | lysine hcl | lysine hydrochloride | lysinum | (s)-2,6-diaminohexanoic acid | (s)-lysine | (s)-α,ε-diaminocaproic acid

Organizations (19)

Research & Development (19)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (10)

Approved Indications (1)


 

Ductus Arteriosus, Patent (approved 2006)

Experimental Indications - Clinical Trial Phases 1-4 (9)


 

Angina Pectoris ()

Anxiety ()

Diabetes Mellitus (Phase 1)

Healthy Volunteers (Phase 1)

Heart Failure (Early Phase 1)

Heroin Dependence ()

Herpes Simplex ()

Osteoporosis ()

Pancreatic Neoplasms (Phase 4)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 20
  • # of Trial Organizations: 19

Trials by Phase

Trial Phase Start Date Organizations Indications

Feedback

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