Active Ingredient History

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Glucose is a sugar with the molecular formula C6H12O6. The D-isomer (D-glucose), also known as dextrose, occurs widely in nature, but the L-isomer (L-glucose) does not. Glucose is made during photosynthesis from water and carbon dioxide, using energy from sunlight. The reverse of the photosynthesis reaction, which releases this energy, is a very important source of power for cellular respiration. Glucose is stored as a polymer, in plants as starch and in animals as glycogen, for times when the organism will need it. Glucose circulates in the blood of animals as blood sugar. Glucose can be obtained by hydrolysis of carbohydrates such as milk, cane sugar, maltose, cellulose, glycogen etc. It is however, manufactured by hydrolysis of cornstarch by steaming and diluting acid. Glucose is the human body's key source of energy, through aerobic respiration, providing about 3.75 kilocalories (16 kilojoules) of food energy per gram. Breakdown of carbohydrates (e.g. starch) yields mono- and disaccharides, most of which is glucose. Use of glucose as an energy source in cells is by either aerobic respiration, anaerobic respiration, or fermentation. All of these processes follow from an earlier metabolic pathway known as glycolysis. The insulin reaction, and other mechanisms, regulate the concentration of glucose in the blood. Glucose supplies almost all the energy for the brain, so its availability influences psychological processes. When glucose is low, psychological processes requiring mental effort (e.g., self-control, effortful decision-making) are impaired. Ingested glucose is absorbed directly into the blood from the intestine and results in a rapid increase in the blood glucose level. Glucose is used to manage hypoglycemia and for intravenous feeding. Nausea may occur after ingesting glucose, but this also may be an effect of the hypoglycemia which is present just prior to ingestion. Other adverse effects include increased blood glucose, injection site leakage of fluid (extravasation), injection site inflammation, and bleeding in the brain.   NCATS

  • SMILES: OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O
  • InChIKey: GZCGUPFRVQAUEE-SLPGGIOYSA-N
  • Mol. Mass: 180.1559
  • ALogP: -3.22
  • ChEMBL Molecules:
More Chemistry

Combination drugs

( amino acids (Freamine), glucose monohydrate - other names: clinimix 2.75/10 sulfite free in dextrose, clinimix 2.75/25 sulfite free in dextrose, clinimix 2.75/5 sulfite free in dextrose, clinimix 4.25/10 sulfite free in dextrose, clinimix 4.25/20 sulfite free in dextrose, clinimix 4.25/25 sulfite free in dextrose, clinimix 4.25/5 sulfite free in dextrose, clinimix 5/10 sulfite free in dextrose, clinimix 5/15 sulfite free in dextrose, clinimix 5/20 sulfite free in dextrose, clinimix 5/25 sulfite free in dextrose, clinimix 5/35 sulfite free in dextrose, travasol in dextrose )
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( magnesium chloride, sodium acetate, amino acids (Freamine), sodium chloride, calcium chloride, potassium phosphate (Tis-U-Sol), glucose monohydrate - other names: clinimix e 2.75/10 sulfite free w/ elect in dextrose w/ calcium, clinimix e 2.75/25 sulfite free w/ elect in dextrose w/ calcium, clinimix e 2.75/5 sulfite free w/ elect in dextrose w/ calcium, clinimix e 4.25/10 sulfite free w/ elect in dextrose w/ calcium, clinimix e 4.25/20 sulfite free w/ elect in dextrose w/ calcium, clinimix e 4.25/5 sulfite free w/ elect in dextrose w/ calcium, clinimix e 5/10 sulfite free w/ elect in dextrose w/ calcium, clinimix e 5/15 sulfite free w/ elect in dextrose w/ calcium, clinimix e 5/20 sulfite free w/ elect in dextrose w/ calcium, clinimix e 5/25 sulfite free w/ elect in dextrose w/ calcium, clinimix e 5/35 sulfite free w/ elect in dextrose w/ calcium )
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( potassium chloride (klor-con), sodium chloride, calcium chloride, glucose monohydrate - other name: dextrose and ringer's )
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( magnesium chloride, sodium acetate, sodium chloride, calcium chloride, glucose monohydrate - other name: dialyte concentrate w/ dextrose )
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( magnesium chloride, lactic acid, sodium chloride, calcium chloride, glucose monohydrate - other names: delflex-lm w/ dextrose, delflex w/ dextrose, delflex w/ dextrose low magnesium, delflex w/ dextrose low magnesium low calcium, dianeal 137 w/ dextrose, dianeal low calcium w/ dextrose, dianeal pd-1 w/ dextrose, dianeal pd-2 w/ dextrose, inpersol-lc/lm w/ dextrose )
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( magnesium chloride, potassium chloride (klor-con), sodium acetate, sodium chloride, glucose monohydrate - other name: isolyte h in dextrose )
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( potassium chloride (klor-con), sodium acetate, sodium chloride, potassium phosphate (Tis-U-Sol), glucose monohydrate - other name: isolyte m in dextrose )
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( magnesium chloride, potassium chloride (klor-con), sodium acetate, sodium chloride, calcium chloride, glucose monohydrate - other name: isolyte r in dextrose )
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( potassium chloride (klor-con), lactic acid, sodium chloride, calcium chloride, glucose monohydrate - other names: dextrose and lactated ringer's, dextrose in half-strength lactated ringer's, dextrose in lactated ringer's, dextrose in modified lactated ringer's, potassium chloride in dextrose and lactated ringer's )
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( potassium acetate, magnesium acetate, sodium chloride, glucose monohydrate - other name: plasma-lyte 56 and dextrose )
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( magnesium chloride, potassium chloride (klor-con), sodium acetate, sodium chloride, glucose monohydrate, sodium gluconate - other names: isolyte s in dextrose, isolyte s w/ dextrose, plasma-lyte 148 and dextrose )
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aldehydo-d-glucose | anhydrous dextrose | capd | clintec | dextro energy | dextrogel | dextrose | dextrose anhydrous | dextrose, anhydrous | dextrose monohydrate | d-glucose | d(+)-glucose | d-glucose, anhydrous | d-glucose in linear form | d-glucose monohydrate | gambrosol | (+)-glucose | glucose monohydrate | glucosemonohydricum | grape sugar | gsf-syrup | rapilose | yourgluco

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