isosorbide (isordil) Report issue

Small molecule Approved FDA Priority Review FDA
AACT ChEMBL DrugBank Drug Central Drugs@FDA KEGG MeSH PubChem repoDB

Active Ingredient History

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Isosorbide dinitrate is a medication used for heart failure, esophageal spasms, and to treat and prevent chest pain from not enough blood flow to the heart. It has been found to be particularly useful in heart failure due to systolic dysfunction together with hydralazine. It is taken by mouth or under the tongue.   Wikipedia

Chemistry

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Pharmacology

Drug Pricing (per unit)

United States

$0.0187 - $17.6948

Australia

$0.0274 - $0.2763
More Pricing Detail

Note: This drug pricing data is preliminary, incomplete, and may contain errors.

Combination drugs

( hydralazine (apresoline), isosorbide (isordil) )

Alternative names

1,4:3,6-dianhydrosorbitol 2,5-dinitrate | 5-ismn | 5-ismn durules | ahr-4698 | angeze 10 | angeze 20 | angeze 40 | angeze sr 40 | angeze sr 60 | angitak | angitate | astridine | astrodur mr | at 101 | at-101 | bm 22.145 | bm-22-145 | carmil xl | carvasin | cedocard | cedocard-10 | cedocard-20 | cedocard-40 | cedocard-5 | cedocard ret | chemydur 60 xl | cibral 10 | cibral 20 | cibral 40 | cibral xl 60 | dianhydrosorbitol 2,5-dinitrate | dilatrate | dilatrate-sr | dinitrate d'isosorbide | dinitrate isosorbide | dinitrato de isosorbida | dinitroisosorbide | dinitrosorbide | (+)-d-isosorbide | d-isosorbide dinitrate | dynamin | dynamin xl 25 | dynamin xl 50 | elantan | elantan 10 | elantan 20 | elantan 40 | elantan la 25 | elantan la 50 | eumon 40 xl | eumon 60 xl | flindix | imdur | imo la | imtack | is 5-mn | is-5mn | is-5-mn | isdn | isib 20 | isib 40 | isib 50 xl | isib 60 xl | ismn | ismo | ismo 10 | ismo 20 | ismo 40 | ismo ret | ismotic | iso-5-mononitrate | isobide | isocard | isodur | isodur 25 xl | isodur 50 xl | isoket 0.05% | isoket 0.1% | isoket 10 | isoket 20 | isoket 5 | isoket ret 20 | isoket ret 40 | iso mack | isorbid | isordil | isordil tembids | isosorbide | isosorbide 2,5-dinitrate | isosorbide 5 mononitrate | isosorbide 5-mononitrate | isosorbide-5-mononitrate | isosorbide 5-nitrate | isosorbide-5-nitrate | isosorbidedinitrate | isosorbide dinitrate | isosorbide mononitrate | isosorbidi dinitras | isosorbidi mononitras | isotard 25 xl | isotard 40 xl | isotard 50 xl | isotard 60 xl | isotrate | jeridin | ketanodur | mcr 50 | modisal 40 xl | modisal 60 xl | modisal la 25 | modisal la 50 | monigen xl 60 | monit | monit ls | monit sr | monit xl 60 | monizid | mono-cedocard 10 | mono-cedocard 20 | mono-cedocard 40 | monocinque | monodur | monoket | mono mac 50d | monomax sr 40 | monomax sr 60 | monomax xl | monomil xl | mononit | mononitrate d'isosorbide | mononitrato de isosorbida | monosorbitrate | monosorb xl 60 | nitrosorbide | olicard 40 | olicard-retard | pertil ret | phasonit la 50 | relosorb xl | r-isosorbide dinitrate | slomon xl 60 | soni-slo | sorbichew | sorbid-20 sa | sorbid-40 sa | sorbide nitrate | sorbidilat | sorbidnitrate | sorbid sa | sorbitrate | tardisc xl | tenkosorb | trangina xl | vascardin | vasotrate 60 sr | xismox xl 60 | zemon 40 xl | zemon 60 xl | ziotan xl

Organizations (130)

Research & Development (96)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (36)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (61)

Approved Indications (5)


 

Angina Pectoris (approved 1993)

Coronary Artery Disease

Glaucoma (approved 1974)

Heart Failure

Ocular Hypertension (approved 1974)

Experimental Indications - Clinical Trial Phases 1-4 (58)


 

Abortion, Induced (Phase 4)

Abortion, Missed (Phase 2)

Acute Coronary Syndrome (Early Phase 1)

Amniotic Fluid (Phase 2/Phase 3)

Angina, Stable (Phase 3)

Angina, Unstable (Phase 4)

Cardio-Renal Syndrome (Phase 3)

Cardiovascular Diseases (Phase 3)

Cerebral Small Vessel Diseases (Phase 2/Phase 3)

Cervical Ripening (Phase 2)

Cognitive Dysfunction (Phase 2)

Contraception (Phase 3)

Coronary Artery Bypass (Phase 4)

Coronary Artery Disease (Phase 4)

Coronary Disease (Phase 4)

Coronary Stenosis (Phase 4)

Diabetic Foot (Phase 3)

Drug-Related Side Effects and Adverse Reactions (Phase 4)

Esophageal and Gastric Varices (Phase 4)

Fetal Development (Phase 4)

Fibrosis (Phase 4)

Fissure in Ano (Phase 4)

Fontan Procedure (Phase 2)

Gastrointestinal Hemorrhage (Phase 4)

Healthy Volunteers (Phase 1)

Heart Diseases (Phase 3)

Heart Failure (Phase 4)

Hemodialysis, Home (Phase 4)

Hypertension (Phase 2)

Hypertension, Portal (Phase 4)

Infertility (Phase 1)

Insulin Resistance (Phase 4)

Intrauterine Devices (Phase 3)

Kidney Diseases (Phase 2)

Labor, Induced (Phase 2)

Labor, Obstetric (Phase 3)

Medicine, Chinese Traditional (Phase 4)

Meniere Disease (Phase 4)

Muscle Spasticity (Phase 4)

Muscular Dystrophy, Duchenne (Phase 1)

Myocardial Infarction (Phase 4)

Myocardial Ischemia (Phase 4)

Orthostatic Intolerance (Phase 1/Phase 2)

Parity (Phase 3)

Pharmacokinetics (Phase 1)

Pilot Projects (Phase 4)

Pregnancy Complications (Phase 4)

Pregnancy, Prolonged (Phase 3)

Prostatic Neoplasms (Phase 1/Phase 2)

Proteinuria (Phase 2)

Shock, Cardiogenic (Phase 4)

Skin Diseases (Phase 1/Phase 2)

Stroke (Phase 2)

Stroke, Lacunar (Phase 2/Phase 3)

Tachycardia (Phase 1/Phase 2)

Therapeutic Equivalency (Phase 1)

Vascular Grafting (Phase 4)

Ventricular Dysfunction, Left (Phase 3)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 77
  • # of Trial Organizations: 96

Trials by Phase

Trial Phase Start Date Organizations Indications

Feedback

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