Active Ingredient History

NOW
  • Now
Polymyxin B is a lipopeptide antibiotic isolated from Bacillus polymyxa. Its basic structure consists of a polycationic peptide ring and a tripeptide side chain with a fatty acid tail. Polymyxin B is a mixture of at least four closely related components, polymyxin B1 to B4, with polymyxin B1 and B2 being the two major components. Polymyxin B acts on Gram-negative bacteria by interacting with lipopolysaccharide (LPS) of the outer membrane and destabilizing it. Polymyxin B is indicated for the treatment of many bacterial diseases such as meningeal infections, urinary tract infections and bacteremia.   NCATS

  • SMILES: CCC(C)CCCCC(=O)N[C@@H](CCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCN)C(=O)N[C@H]1CCNC(=O)[C@@H](NC(=O)[C@H](CCN)NC(=O)[C@H](CCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](CCN)NC1=O)[C@@H](C)O.OS(=O)(=O)O
  • InChIKey: HFMDLUQUEXNBOP-OLYKAHIFSA-N
  • Mol. Mass: 1301.58
  • ALogP: Missing data
  • ChEMBL Molecules:
More Chemistry
  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Prescription Only
  • Delivery Methods: Missing data
  • Pro Drug: No

Drug Pricing (per unit)

More Pricing Detail

Note: This drug pricing data is preliminary, incomplete, and may contain errors.

Combination drugs

( urea, neomycin, polymyxin b sulfate (poly-rx) - other names: neomycin and polymyxin b sulfates and hydrocortisone, oticair, pediotic )
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( urea, bacitracin (polysporin), neomycin, polymyxin b sulfate (poly-rx) - other names: bacitracin-neomycin-polymyxin w/ hydrocortisone acetate, neomycin and polymyxin b sulfates, bacitracin zinc and hydrocortisone )
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( neomycin, polymyxin b sulfate (poly-rx), dexamethasone - other names: dexacidin, dexasporin, neomycin and polymyxin b sulfates and dexamethasone )
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( bacitracin (polysporin), neomycin, polymyxin b sulfate (poly-rx) - other name: neomycin and polymyxin b sulfates and bacitracin zinc )
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( neomycin, polymyxin b sulfate (poly-rx), gramicidin - other name: neomycin and polymyxin b sulfates and gramicidin )
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( neomycin, polymyxin b sulfate (poly-rx) - other names: neomycin and polymyxin b sulfate, statrol )
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( urea, polymyxin b sulfate (poly-rx) - other name: otobiotic )
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( polymyxin b sulfate (poly-rx), oxytetracycline (terramycin) )
aerosporin | bacitracin - polymyxin b | bacitracin, polymyxin b drug combination | duobiotic | gppe pdr ster | mastimyxin | neosporin | polimixina b | polyfax | polymycin b sulfate | polymyxin | polymyxin b | polymyxin b(1) | polymyxin-b-sulfat | polymyxin b sulfate | polymyxin b sulphate | polymyxine b | polymyxine b (sulfate de) | polymyxini b sulfas | polymyxinum b | poly-rx | polysporin | polytrim | thiosporin

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