Active Ingredient History

  • Now
Lomustine is used in the treatment of certain neoplastic diseases. Although it is generally agreed that lomustine alkylates DNA and RNA, it is not cross resistant with other alkylators. As with other nitrosoureas, it may also inhibit several key enzymatic processes by carbamoylation of amino acids in proteins. Common adverse reactions include delayed myelosupression, nausea, vomiting, stomatitis, and alopecia.   NCATS

  • Mol. Mass: 233.695
  • ALogP: 2.25
  • ChEMBL Molecule:
More Chemistry
  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: Yes
  • Availability: Prescription Only
  • Delivery Methods: Oral
  • Pro Drug: No
1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea | 1-(2-chloroethyl)-3-cyclohexylnitrosourea | belustine | ccnu | cecenu | ceenu | chloroethylcyclohexylnitrosourea | cinu | cyclohexyl chloroethyl nitrosourea | lomustin | lomustina | lomustine | lomustinum | n-(2-chloroethyl)-n'-cyclohexyl-n-nitrosourea


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