aprepitant (Emend) Report issue

Small molecule Approved FDA Priority Review FDA
AACT ChEMBL DrugBank Drug Central Drugs@FDA KEGG MeSH PubChem repoDB

Active Ingredient History

NOW
  • Now
Fosaprepitant is an antiemetic medication, administered intravenously. It is a prodrug of aprepitant.   Wikipedia

Chemistry

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Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Prescription Only
  • Delivery Methods: Parenteral
  • Pro Drug: Yes

Drug Pricing (per unit)

United States

$0.2837 - $322.9300

Australia

$51.9296 - $80.9956
More Pricing Detail

Note: This drug pricing data is preliminary, incomplete, and may contain errors.

Alternative names

(1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(fluoro)phenyl-4-(3-oxo-1,2,4-triazol-5-yl)methylmorpholine | ((2r)-(1r)-3,5-bis(trifluoromethyl)phenylethoxy)-3-(s)-(4-fluoro)phenyl-4-(3-(1-phosphoryl-5-oxo-4h-1,2,4-triazolo))methylmorpholine | (2r)-(1r)-3,5-bis(trifluoromethylphenyl)ethoxy)-(3s)-(4-fluoro)phenyl-4-(3-(5-oxo-1h,4h-1,2,4-triazole)methyl-morpholine | 3-(((2r,3s)-3-(p-fluorophenyl)-2-(((alphar)-alpha-methyl-3,5-bis(trifluoromethyl)benzyl)oxy)morpholino)methyl)-delta(2)-1,2,4-triazolin-5-one | aprepitant | aprépitant | aprepitantum | apretpitant | emend | emend for injection | fosaprepitant | fosaprepitant dimeglumine | fosaprepitant meglumine | fosaprepitantum | ivemend | l 754030 | l 754,030 | l-754030 | l-754,030 | l758298 | l 758298 | l-758,298 | l 785,298 | l-785,298 | l785,298 | mk0517 | mk 0517 | mk-0517 | mk0869 | mk 0869 | mk-0869 | mk 869 | mk-869 | ono-7436

Organizations (182)

Research & Development (161)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (24)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (60)

Approved Indications (4)


 

Leukemia, Myeloid, Acute

Nausea (approved 2008)

Neoplasms

Postoperative Nausea and Vomiting

Experimental Indications - Clinical Trial Phases 1-4 (60)


 

Alcoholism (Phase 2)

Analgesia (Phase 2)

Bile Duct Neoplasms (Phase 2)

Brain Injuries, Traumatic (Early Phase 1)

Breast Neoplasms (Phase 4)

Cannabis (Phase 2)

Carcinoma, Non-Small-Cell Lung (Phase 3)

Cervical Intraepithelial Neoplasia (Phase 2)

Cholangiocarcinoma (Phase 2)

Cocaine-Related Disorders (Phase 2)

Colorectal Neoplasms (Phase 3)

COVID-19 (Phase 2)

Depressive Disorder, Major (Phase 3)

Diabetes Mellitus, Type 2 (Phase 2)

Drug-Related Side Effects and Adverse Reactions (Phase 4)

Drug Therapy (Phase 2)

Gastrointestinal Neoplasms (Phase 2)

Gastroparesis (Phase 3)

General Surgery (Phase 3)

Genital Neoplasms, Female (Phase 3)

Glioblastoma (Phase 1)

Glioma (Phase 2)

Head and Neck Neoplasms (Phase 2)

Healthy Volunteers (Phase 4)

Heart Failure (Phase 4)

Hematologic Diseases (Phase 2)

Heroin Dependence (Phase 1)

HIV Infections (Phase 1)

Hypertension (Phase 2)

Laparoscopy (Phase 4)

Leukemia (Phase 4)

Leukemia, Myelogenous, Chronic, BCR-ABL Positive (Phase 2)

Leukemia, Myeloid, Acute (Phase 3)

Lung Neoplasms (Phase 2)

Lymphoma (Phase 4)

Lymphoma, Non-Hodgkin (Phase 1)

Marijuana Abuse (Phase 2)

Multiple Myeloma (Phase 3)

Myelodysplastic Syndromes (Phase 2)

Myeloproliferative Disorders (Phase 3)

Nasopharyngeal Carcinoma (Phase 1)

Nausea ()

Neoadjuvant Therapy (Phase 2)

Neoplasms ()

Neoplasms, Germ Cell and Embryonal (Phase 3)

Opioid-Related Disorders (Phase 1)

Ovarian Neoplasms (Phase 4)

Pancreatic Neoplasms (Phase 3)

Parkinson Disease (Phase 2)

Postoperative Complications (Phase 4)

Postoperative Nausea and Vomiting ()

Pruritus (Phase 4)

Sarcoma (Phase 2)

Sezary Syndrome (Phase 4)

Stress Disorders, Post-Traumatic (Phase 2)

Substance-Related Disorders (Phase 1)

Substance Withdrawal Syndrome (Phase 1)

Tobacco Use Disorder (Phase 1)

Uterine Neoplasms (Phase 4)

Vomiting (Phase 4)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 200
  • # of Trial Organizations: 161

Trials by Phase

Trial Phase Start Date Organizations Indications

Feedback

Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).

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