Active Ingredient History

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Hexachlorophene, also known as Nabac, is an organochlorine compound that was once widely used as a disinfectant. The compound occurs as a white odorless solid, although commercial samples can be off-white and possess a slightly phenolic odor. It is insoluble in water but dissolves in acetone, ethanol, diethyl ether, and chloroform. Exact mechanism(s) of action unknown, but at low concentrations appears to interrupt bacterial electron transport and inhibit membrane-bound enzymes. Higher concentrations rupture bacterial membranes. It induces leakage, causes protoplast lysis, and inhibits respiration. In medicine, hexachlorophene is a useful as a topical anti-infective, anti-bacterial agent, often used in soaps and toothpaste. It is also used in agriculture as a soil fungicide, plant bactericide, and acaricide.   NCATS

More Chemistry
2,2',3,3',5,5'-hexachloro-6,6'-dihydroxydiphenylmethane | 2,2'-dihydroxy-3,3',5,5',6,6'-hexachlorodiphenylmethane | 2,2'-dihydroxy-3,5,6,3',5',6'-hexachlorodiphenylmethane | 2,2'-methanediylbis(3,4,6-trichlorophenol) | 2,2'-methylenebis(3,4,6-trichlorophenol) | almederm | bis(2-hydroxy-3,5,6-trichlorophenyl)methane | bis(3,5,6-trichloro-2-hydroxyphenyl)methane | ch-3565 | cloxifenol | dermadex | dndi1246774 | exofene | fomac | gamophen | gamophene | germa-medica | germa-medica mg | hexachlorofen | hexachlorophen | hexachlorophene | hexachlorophène | hexachlorophenum | hexaclorofeno | hexa-germ | hexascrub | hexophene | phisohex | phiso-scrub | pre-op | pre-op ii | scrubteam surgical spongebrush | septi-soft | septisol | soy-dome | turgex


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