Active Ingredient History

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Pramipexole is a nonergot dopamine agonist with high relative in vitro specificity and full intrinsic activity at the D2 subfamily of dopamine receptors, binding with higher affinity to D3 than to D2 or D4 receptor subtypes. The relevance of D3 receptor binding in Parkinson's disease is unknown. The precise mechanism of action of Pramipexole as a treatment for Parkinson's disease is unknown, although it is believed to be related to its ability to stimulate dopamine receptors in the striatum. This conclusion is supported by electrophysiologic studies in animals that have demonstrated that Pramipexole influences striatal neuronal firing rates via activation of dopamine receptors in the striatum and the substantia nigra, the site of neurons that send projections to the striatum. Pramipexole is used for the treatment of signs and symptoms of idiopathic Parkinson's disease.   NCATS

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Drug Pricing (per unit)

United States

$0.0447 - $21.2537


$0.0762 - $2.5828
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Note: This drug pricing data is preliminary, incomplete, and may contain errors.

2,6-benzothiazolediamine, 4,5,6,7-tetrahydro-n6-propyl-, (s)- | 2,6-benzothiazolediamine, 4,5,6,7-tetrahydro-n(sup 6)-propyl-, (s)- | 2-amino-4,5,6,7-tetrahydro-6-propylaminobenzothiazole | 2-amino-6-allyl-5,6,7,8-tetrahydro-4h-thiazolo-(5,4-d)azepin-dihydrochloride | 2-amino-6-propylaminotetrahydrobenzothiazole | 4,5,6,7-tetrahydro-n6-propyl-2,6-benzothiazole-diamine | 4h-thiazolo(4,5-d)azepin-2-amine, 5,6,7,8-tetrahydro-6-(2-propenyl)-, dihydrochloride | 6,7-tetrahydro-n6-propyl-2,6-benzothiazolediamine dihydrochloride monohydrate | 6-allyl-2-amino-5,6,7,8-tetrahydro-4h-thiazolo(4,5-d)azepin dihydrochloride | bht920 | b ht920 | b-ht 920 | bht 920 | domin | kns760704 | kns 760704 | kns-760704 | mirapex | mirapex er | mirapex extended release | mirapexin | neliprax | oprymea | pipexus | pnu-98528e | pramipexol | pramipexol dihydrobromide | pramipexol dihydrobromide, (+-)-isomer | pramipexol dihydrochloride, (s)-isomer | pramipexole | (-)-pramipexole | pramipexole dihydrochloride | pramipexole dihydrochloride monohydrate | pramipexole hcl | pramipexole hydrochloride | pramipexole hydrochloride hydrate | pramipexol, (+-)-isomer | pramipexol, (r)-isomer | pramipexolum | sifrol | sifrole | (s)-n  6-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine | snd-919 | snd919cl2x | snd 919cl2x | snd-919cl2x | snd919cl2y | snd-919cl2y | (s)-pramipexole | sud-919cl2y | talipexole | talipexole hcl | talipexole hydrochloride | u-98528e


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