Active Ingredient History

  • Now
Methylnaltrexone, is a peripherally acting μ-opioid receptor antagonist that acts on the gastrointestinal tract to inhibit the opioid-induced decrease in gastric motility and transit time. It is used to treat opiate-induced constipation in adults with chronic non-cancer pain and in adults with advanced illness who are receiving palliative care.   NCATS

  • SMILES: C[N+]1(CC2CC2)CC[C@]34[C@H]5Oc6c(O)ccc(C[C@@H]1[C@]3(O)CCC5=O)c46
  • Mol. Mass: 356.44
  • ALogP: 1.67
  • ChEMBL Molecules:
More Chemistry
  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Prescription Only
  • Delivery Methods: Oral, Parenteral
  • Pro Drug: No

Drug Pricing (per unit)

United States

$4.1710 - $129.1190


$24.9492 - $24.9503
More Pricing Detail

Note: This drug pricing data is preliminary, incomplete, and may contain errors.

17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinanium-6-one | (5alpha)-17-(cyclopropylmethyl)-3,14-dihydroxy-17-methyl-4,5-epoxymorphinan-17-ium-6-one | methylnaltrexone | methylnaltrexone bromide | methyl-naltrexone hydrobromide | methylnaltrexonium | mntx | morphinan-17-ium-6-one, 17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxy-17-methyl-, (5alpha)- | morphinan-17-ium-6-one, 17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxy-17-methyl-, bromide, (5alpha,17r)- | morphinanium, 17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxy-17-methyl-6-oxo-, (5alpha)- | mrz-2663 | mrz 2663br | mrz-2663br | naltrexone mb | naltrexone methobromide | naltrexone methylbromide | naltrexonium methiodide | n-methylnaltrexone bromide | quaternary ammonium naltrexone | relistor


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