Active Ingredient History

  • Now
Melphalan, also known as L-phenylalanine mustard, phenylalanine mustard, L-PAM, or L-sarcolysin, is a phenylalanine derivative of nitrogen mustard. Melphalan is a bifunctional alkylating agent which produces a number of DNA adducts with the DNA interstrand crosslink (ICL) considered to be the critical cytotoxic lesion. Melphalan is used to treat different cancers including myeloma, melanoma and ovarian cancer.   NCATS

  • SMILES: N[C@@H](Cc1ccc(cc1)N(CCCl)CCCl)C(=O)O
  • Mol. Mass: 305.21
  • ALogP: 1.93
  • ChEMBL Molecules:
More Chemistry
  • Mechanisms of Action:
  • Multi-specific: Missing data
  • Black Box: Yes
  • Availability: Prescription Only
  • Delivery Methods: Oral, Parenteral
  • Pro Drug: No

Drug Pricing (per unit)

United States

$7.3438 - $848.8900
More Pricing Detail

Note: This drug pricing data is preliminary, incomplete, and may contain errors.

3-(p-(bis(2-chloroethyl)amino)phenyl)-l-alanine | 3-p-(di(2-chloroethyl)amino)-phenyl-l-alanine | 4-(bis(2-chloroethyl)amino)-l-phenylalanine | aikeran | alanine nitrogen mustard | alkeran | cb-3025 | l-3-(p-(bis(2-chloroethyl)amino)phenyl)alanine | levofalan | levofolan | levopholan | l-pam | l-phenylalanine mustard | l-sarcolysin | l-sarcolysine | melfalan | melfalano | melflufen | melphalan | melphalan-flufenamide | melphalan hcl | melphalan hydrochloride | melphalanum | p-bis(beta-chloroethyl)aminophenylalanine | p-di-(2-chloroethyl)amino-l-phenylalanine | phenylalanine mustard | phenylalanine nitrogen mustard | p-l-sarcolysin | p-n-bis(2-chloroethyl)amino-l-phenylalanine | p-n,n-bis(2-chloroethyl)amino-l-phenylalanine | sarcoclorin


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