Active Ingredient History

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Zoliflodacin is an experimental antibiotic that is being studied for the treatment of infection with Neisseria gonorrhoeae (gonorrhea). It has a novel mechanism of action which involves inhibition of bacterial type II topoisomerases. It is being developed by Entasis Therapeutics and is in Phase III clinical trials.   Wikipedia

  • SMILES: C[C@@H]1CN2[C@H]([C@H](C)O1)C3(Cc4cc5c(noc5c(F)c24)N6[C@@H](C)COC6=O)C(=O)NC(=O)NC3=O
  • Mol. Mass: 487.44
  • ALogP: 1.2
  • ChEMBL Molecule:
More Chemistry
azd0914 | azd-0914 | etx-0914 | zoliflodacin


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