tivozanib (Fotivda) Report issue

Small molecule Approved FDA
AACT ChEMBL DrugBank MeSH PubChem

Active Ingredient History

NOW
  • Now
Tivozanib, sold under the brand name Fotivda, is a medication used for the treatment of relapsed or refractory advanced renal cell carcinoma (RCC). It is an oral VEGF receptor tyrosine kinase inhibitor.   Wikipedia

Chemistry

  • SMILES: COc1cc2nccc(Oc3ccc(NC(=O)Nc4cc(C)on4)c(Cl)c3)c2cc1OC
  • InChIKey: SPMVMDHWKHCIDT-UHFFFAOYSA-N
  • Mol. Mass: 454.87
  • ALogP: 5.64
  • ChEMBL Molecules:
    tivozanib  
    tivozanib hydrochloride  
More Chemistry

Pharmacology

Alternative names

asp-4130 | av 951 | av-951 | av951 cpd | kil8951 | kil-8951 | krn951 | krn 951 | krn-951 | tivozanib | tivozanib hcl | tivozanib hydrochloride

Organizations (25)

Research & Development (25)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (1)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (26)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (26)


 

Bile Duct Neoplasms (Phase 1/Phase 2)

Biliary Tract Neoplasms (Phase 2)

Breast Neoplasms (Phase 1/Phase 2)

Carcinoma, Hepatocellular (Phase 2)

Carcinoma, Non-Small-Cell Lung (Phase 1/Phase 2)

Carcinoma, Renal Cell (Phase 3)

Cholangiocarcinoma (Phase 1/Phase 2)

Colorectal Neoplasms (Phase 2)

Epidermal Growth Factor (Phase 2)

Fallopian Tube Neoplasms (Phase 2)

Gallbladder Neoplasms (Phase 1/Phase 2)

Gastrointestinal Neoplasms (Phase 1/Phase 2)

Glioblastoma (Phase 2)

Hamartoma (Phase 2)

Healthy Volunteers (Phase 1)

Liver Diseases (Phase 1)

Liver Neoplasms (Phase 2)

Neoplasms ()

Neuroendocrine Tumors (Phase 1/Phase 2)

Ovarian Neoplasms (Phase 2)

Pancreatic Neoplasms (Phase 2)

Pharmacology (Phase 1)

Prostatic Neoplasms (Phase 2)

Sarcoma (Phase 2)

Triple Negative Breast Neoplasms (Phase 2)

Vulvar Neoplasms (Phase 1/Phase 2)

Overview

  • Highest Phase: Phase 3
  • # of Trials: 36
  • # of Trial Organizations: 25

Trials by Phase

Trial Phase Start Date Organizations Indications

Feedback

Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).

Report issue