Active Ingredient History

  • Now
Mibampator is a positive allosteric modulator (PAM) of the AMPA receptor (AMPAR), an ionotropic glutamate receptor, which was under development by Eli Lilly for the treatment of agitation/aggression in Alzheimer's disease but was never marketed. It reached phase II clinical trials prior to the discontinuation of its development.   Wikipedia

  • SMILES: CC(C)S(=O)(=O)NC[C@H](C)c1ccc(cc1)c2ccc(CCNS(=O)(=O)C)cc2
  • Mol. Mass: 438.62
  • ALogP: 2.88
  • ChEMBL Molecule:
More Chemistry
ly451395 | ly 451395 | ly-451395 | mibampator | n-((2-(4'-(2-(methylsulfonyl)amino)ethyl)(1,1'-biphenyl)-4-yl)propyl)-2-propanesulfonamide


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