Active Ingredient History

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Meclinertant (SR-48692) is a drug which acts as a selective, non-peptide antagonist at the neurotensin receptor NTS1, and was the first non-peptide antagonist developed for this receptor. It is used in scientific research to explore the interaction between neurotensin and other neurotransmitters in the brain, and produces anxiolytic, anti-addictive and memory-impairing effects in animal studies.   Wikipedia

  • SMILES: COc1cccc(OC)c1c2cc(nn2c3ccnc4cc(Cl)ccc34)C(=O)NC5(C6CC7CC(CC5C7)C6)C(=O)O
  • Mol. Mass: 587.08
  • ALogP: 5.77
  • ChEMBL Molecule:
More Chemistry
2-((1-(7-chloro-4-quinolinyl)-5-(2,6-dimethoxyphenyl)pyrazol-3-yl)carbonylamino)tricyclo( acid | meclinertant | reminertant | sr48692 | sr 48692 | sr-48692 | tricyclo(,7)decane-2-carboxylic acid, 2-(((1-(7-chloro-4-quinolinyl)-5-(2,6-dimethoxyphenyl)-1h-pyrazol-3-yl)carbonyl)amino)-


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