Active Ingredient History

  • Now
AMOBARBITAL is a barbiturate derivative with hypnotic and sedative properties. In an in vitro study in rat thalamic slices amobarbital worked by activating GABAA receptors, which decreased input resistance, depressed burst and tonic firing, especially in ventrobasal and intralaminar neurons, while at the same time increasing burst duration and mean conductance at individual chloride channels; this increased both the amplitude and decay time of inhibitory postsynaptic currents. Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with continued use is high.   NCATS

More Chemistry
  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Missing data
  • Delivery Methods: Missing data
  • Pro Drug: No
5-ethyl-5-(3-methylbutyl)-2,4,6(1h,3h,5h)-pyrimidinetrione | 5-ethyl-5-(3-methylbutyl)barbituric acid | 5-ethyl-5-isoamylbarbituric acid | 5-ethyl-5-isopentylbarbituric acid | amobarbital | amobarbital sodium | amobarbital sodium for injection | amobarbitone | amylbarbitone | amylobarbital | amylobarbitone | amytal | amytal sodium | barbamil | barbamyl | barbamyl acid | ethylisopentylbarbituric acid | isoamylethylbarbituric acid | isopentobarbital | pentymal | sod amytal | talamo


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