Active Ingredient History

  • Now
Paramethadione is an anticonvulsant in the oxazolidinedione class developed by the Abbott Laboratories, approved by the Food and Drug Administration in 1949 for the treatment of absence seizures, also called partial seizures. Paramethadione acts to reduce T-type calcium currents in thalamic neurons which has been proposed to underlie the 3-Hz spike-and-wave discharge seen on electroencephalogram (EEG) during absence seizures.   NCATS

  • Mol. Mass: 157.1671
  • ALogP: 0.76
  • ChEMBL Molecule:
More Chemistry
5-ethyl-3,5-dimethyloxazolinedione | isoethadione | paradione | parametadiona | parametadione | paramethadione | paramethadionum


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