Active Ingredient History

  • Now
Chlorobutanol, or trichloro-2-methyl-2-propanol, is an analgesic and sedative hypnotic in man, and an experimental general anesthetic. It has antibacterial and antifungal properties. It is also used chemical preservative for parenteral drugs. It was found, that chlorobutanol inhibited mammalian Nav 1.2 channels at concentrations less than those used to preserve parenteral solutions. Its mechanism of inhibiting Na channels differs from that of local anesthetics in that it does not show use dependent or state dependent inhibition.   NCATS

  • SMILES: CC(C)(O)C(Cl)(Cl)Cl
  • Mol. Mass: 177.457
  • ALogP: 2.13
  • ChEMBL Molecule:
More Chemistry
  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Missing data
  • Delivery Methods: Missing data
  • Pro Drug: No
acetochlorone | acetonchloroform | acetone chloroform | chlorbutanol | chlorbutol | chloreton | chloretone | chlorobutanol | trichlorisobutylalcohol | trichlorobutanol | trichlor-tertiary-butyl-alcohol


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