Active Ingredient History

  • Now
Dicumarol is an coumarin-like compound found in sweet clover. It is used as oral anticoagulant and acts by inhibiting the hepatic synthesis of vitamin K-dependent coagulation factors (prothrombin and factors VII, IX, and X). It results in decresed prothrombin levels and a decrease in the amount of thrombin generated and bound to fibrin. This reduces the thrombogenicity of clots. Dicumarol is also used in biochemical experiments as an inhibitor of reductases.   NCATS

  • SMILES: OC1=C(CC2=C(O)C3=C(OC2=O)C=CC=C3)C(=O)OC4=C1C=CC=C4
  • Mol. Mass: 336.295
  • ALogP: 2.9
  • ChEMBL Molecule:
More Chemistry
  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Discontinued
  • Delivery Methods: Oral
  • Pro Drug: No
3,3'-methylen-bis(4-hydroxy-cumarin) | 3,3'-methylenebis(4-hydroxy-1,2-benzopyrone) | 3,3'-methylenebis(4-hydroxy-2h-1-benzopyran-2-one) | 3,3'-methylenebis(4-hydroxycoumarin) | 3,3'-methylene-bis(4-hydroxycoumarine) | bis-3,3'-(4-hydroxycoumarinyl)methane | bis(4-hydroxycoumarin-3-yl)methane | bishydroxycoumarin | bis-hydroxycoumarin | di-(4-hydroxy-3-coumarinyl)methane | dicoumal | dicoumarin | dicoumarol | dicoumarolum | dicuman | dicumarine | dicumarol | trombosan


Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).

Report issue