Active Ingredient History

Barbital, the one of the series of barbiturates, has hypnotic, sedative, and anticonvulsant properties and used under the trade name Veronal. It calmed manic patients and helped melancholic patients to sleep and was an effective inducer of sleep in insomniacs, but at the same time compound could induced dependence. It was substituted by the butyl analog, butobarbital, which was three times stronger and its period of action was much shorter due to its lipophilicity. Barbital is a ligand of GABA-receptor complex and in addition, it could have another target, a creatine kinase.   NCATS

  • SMILES: CCC1(CC)C(=O)NC(=O)NC1=O
  • InChIKey: FTOAOBMCPZCFFF-UHFFFAOYSA-N
  • Mol. Mass: 184.19
  • ALogP: 0.16
  • ChEMBL Molecules:
More Chemistry
  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Missing data
  • Delivery Methods: Missing data
  • Pro Drug: No
barbital | barbital sodium | barbital, soluble | barbitone | barbitone sodium | diemal | diethylbarbitone | diethylbarbituric acid | diethylmalonylurea | ethylbarbital | sodium diethylbarbiturate | veronal

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