Active Ingredient History

  • Now
Telenzepine is a thienobenzodiazepine acting as selective M1 antimuscarinic. It is used in the treatment of peptic ulcers. Telenzepine is atropisomeric, in other words the molecule has a stereogenic C–N-axis. In neutral aqueous solution it displays a half-life for racemization of the order of 1000 years. The enantiomers have been resolved. The activity is related to the (+)-isomer which is about 500-fold more active than the (–)-isomer at muscarinic receptors in the rat cerebral cortex.   Wikipedia

  • SMILES: CN1CCN(CC(=O)N2c3ccccc3NC(=O)c4csc(C)c24)CC1
  • Mol. Mass: 370.48
  • ALogP: 2.53
  • ChEMBL Molecule:
More Chemistry
4,9-dihydro-3-methyl-4-((4-methyl-1-piperazinyl)acetyl)-10h-thieno(3,4-b)(1,5)benzodiazepin-10-one | telenzepine


Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).

Report issue