Active Ingredient History

  • Now
Bacampicillin is a penicillin antibiotic. It is a prodrug of ampicillin with improved oral bioavailability. It exerts bactericidal activity via inhibition of bacterial cell wall synthesis by binding one or more of the penicillin binding proteins (PBPs). Spectrobid is used to treat bacterial infections such as tonsillitis, pneumonia (lung infection), bronchitis (inflammation of airway), urinary tract infections, gonorrhea, and infections of the skin. Adverse effects are: anemia, thrombocytopenia, neutropenia, agranulocytosis, seizures, nephrotoxicity, Jarisch-Herxheimer Reaction (fever, chills, sweating, tachycardia, hyperventilation, flushing, and myalgia). Drug interactions: Contraceptives - decreased contraceptive effectiveness; Live Typhoid Vaccine - decreased immunological response to the typhoid vaccine; Probenecid - increased bacampicillin levels.   NCATS

  • SMILES: CCOC(=O)OC(C)OC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](NC(=O)[C@H](N)c3ccccc3)C2=O
  • Mol. Mass: 465.53
  • ALogP: 1.3
  • ChEMBL Molecules:
More Chemistry
1-[(ethoxycarbonyl)oxy]ethyl (2s,5r,6r)-6-{[(2r)-2-amino-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate | 1'-ethoxycarbonyloxyethyl-(6-d-alpha-aminophenylacetamido)penicillanate | ambaxin | bacampicilina | bacampicillin | bacampicilline | bacampicillin hcl | bacampicillin hydrochloride | bacampicillin monohydrochloride | bacampicillinum | bacampicine | carampicillin | ethoxycarbonyloxyethyl ester of ampicillin | penglobe | spectrobid


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