Active Ingredient History

  • Now
Tranexamic acid is an antifibrinolytic that competitively inhibits the activation of plasminogen to plasmin. Tranexamic acid is a competitive inhibitor of plasminogen activation, and at much higher concentrations, a noncompetitive inhibitor of plasmin, i.e., actions similar to aminocaproic acid. Tranexamic acid is about 10 times more potent in vitro than aminocaproic acid. Tranexamic acid binds more strongly than aminocaproic acid to both the strong and weak receptor sites of the plasminogen molecule in a ratio corresponding to the difference in potency between the compounds. Tranexamic acid in a concentration of 1 mg per mL does not aggregate platelets in vitro. In patients with hereditary angioedema, inhibition of the formation and activity of plasmin by tranexamic acid may prevent attacks of angioedema by decreasing plasmin-induced activation of the first complement protein (C1). Tranexamic acid is used for use in patients with hemophilia for short term use (two to eight days) to reduce or prevent hemorrhage and reduce the need for replacement therapy during and following tooth extraction. It can also be used for excessive bleeding in menstruation, surgery, or trauma cases.   NCATS

  • SMILES: NC[C@H]1CC[C@@H](CC1)C(O)=O
  • Mol. Mass: 157.2102
  • ALogP: -0.08
  • ChEMBL Molecules:
More Chemistry
  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Prescription Only
  • Delivery Methods: Missing data
  • Pro Drug: No

Drug Pricing (per unit)

United States

$0.3110 - $30.1490
More Pricing Detail

Note: This drug pricing data is preliminary, incomplete, and may contain errors.

acide tranexamique | acido tranexamico | acidum tranexamicum | amchafibrin | amikapron | cl-65336 | cyclocapron | cyclokapron | cyklo-f heavy period relief | cyklokapron | exacyl | lb1148 | lysteda | menstralite | ranelic acid | traexamic acid | tranexamic acid | tranexaminic acid | tranexamsaeure | tranexmic acid | tranhexamic acid | tranol | trans-4-aminomethylcyclohexane-1-carboxylic acid | trans-4-(aminomethyl)cyclohexanecarboxylic acid | trans amcha | trans-amcha | transamin | trans-tranexamic acid | zataranax


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