Active Ingredient History

  • Now
Norelgestromin, the progestin, is the active metabolite of norgestimate and is structurally related to 19-nortestosterone. Norgestimate and norelgestromin mimic the physiologic effects of progesterone at the progesterone receptor. Johnson & Johnson developed an adhesive female contraceptive patch that contains ethinylestradiol (0.75mg) and the progestogen norelgestromin (6mg). his product is a combination contraceptive acting via the inhibition gonadotropins. Its primary mechanism of action involves the suppression of ovulation, including changes in the cervical mucus and endometrium. The patch delivers a continuous flow of hormones through the skin and into the bloodstream. The contraceptive patch is available in countries worldwide.   NCATS

  • SMILES: CC[C@]12CC[C@H]3[C@@H](CCC4=CC(CC[C@H]34)=NO)[C@@H]1CC[C@@]2(O)C#C
  • Mol. Mass: 327.4605
  • ALogP: 4.14
  • ChEMBL Molecule:
More Chemistry
  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: Yes
  • Availability: Prescription Only
  • Delivery Methods: Topical
  • Pro Drug: No

Combination drugs

( ethinyl estradiol (Estinyl), norelgestromin (Evra) - other name: xulane )
17-deacetylnorgestimate | 17-deacylnorgestimate | 18-methylnorethindrone oxime | brn 4202099 | deacetylnorgestimate | d-norgestrel 3-oxime | evra | levonorgestrel 3-oxime | levonorgestrel oxime | levonorgestrel oxime, (3e,17alpha)-isomer | levonorgestrel oxime, (3z,17alpha)-isomer | lngo | norelgestromin | norelgestromin / ethinyl estradiol | norelgestromin-ethinyl estradiol combination patch | norplant 3-oxime | ortho evra | progestin norelgestromin | rwj-10553


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