Active Ingredient History
Sildenafil (Viagra, Revatio) is a PDE5 inhibitor which was approved by FDA for the treatment of erectile disfunction and adults with pulmonary arterial hypertension. Upon administration sildenafil inhibits PDE5 and results in elevated level of cyclic guanosine monophosphate and smooth muscle relaxation. NCATS
Drug Pricing (per unit)
Note: This drug pricing data is preliminary, incomplete, and may contain errors.
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
Hypertension, Pulmonary (approved 2005)
Abortion, Habitual (Phase 4)
Acute Febrile Encephalopathy (Phase 1)
Acute Kidney Injury (Phase 1)
Altitude Sickness (Phase 4)
Anemia, Sickle Cell (Phase 4)
Aneurysm (Phase 2)
Angina Pectoris (Phase 4)
Anticoagulants (Phase 1)
Aortic Valve Stenosis (Phase 4)
Arterial Occlusive Diseases (Phase 3)
Arteriovenous Anastomosis (Early Phase 1)
Arthritis, Rheumatoid (Phase 2)
Atherosclerosis (Phase 2)
Bacterial Infections (Phase 1/Phase 2)
Blindness (Phase 4)
Blood Pressure (Phase 2)
Brain Concussion (Phase 2)
Brain Injuries, Traumatic (Phase 2)
Brain Neoplasms (Phase 2)
Breast Neoplasms (Phase 1)
Bronchopulmonary Dysplasia (Phase 2)
Carcinoma, Non-Small-Cell Lung (Phase 2/Phase 3)
Cardiopulmonary Bypass (Phase 4)
Cardiovascular Diseases (Phase 2/Phase 3)
Central Serous Chorioretinopathy (Phase 2)
Cerebrovascular Disorders (Phase 2)
Cholangiocarcinoma (Phase 1)
Coronary Artery Disease (Phase 1)
Coronary Vasospasm (Phase 3)
COVID-19 (Phase 3)
Cystic Fibrosis (Phase 2/Phase 3)
Depression (Phase 4)
Dermatology (Early Phase 1)
Dermatomyositis (Early Phase 1)
Diabetes Mellitus (Phase 4)
Diabetes Mellitus, Type 2 (Phase 4)
Diabetic Neuropathies (Phase 4)
Diving (Phase 2)
Drugs, Investigational (Phase 2/Phase 3)
Dysmenorrhea (Phase 1/Phase 2)
Edema (Early Phase 1)
Eisenmenger Complex (Phase 3)
Emphysema (Phase 4)
Endometrium (Phase 4)
Endothelial Cells (Phase 4)
Ethnic and Racial Minorities (Early Phase 1)
Fatigue Syndrome, Chronic (Phase 4)
Fertilization in Vitro (Phase 4)
Fetal Development (Phase 4)
Fetal Distress (Phase 4)
Fetal Growth Retardation (Phase 3)
Fibrosis (Phase 1)
Fontan Procedure (Phase 4)
Foramen Ovale, Patent (Early Phase 1)
Gastrointestinal Neoplasms (Phase 1)
General Surgery (Phase 4)
Genetic Diseases, Inborn (Phase 1)
Genital Neoplasms, Female (Phase 1)
Glaucoma (Phase 3)
Glioblastoma (Phase 2)
Glioma (Phase 2)
Glucose Intolerance (Phase 4)
Growth and Development (Phase 3)
Hand-Foot Syndrome (Phase 1)
Healthy Volunteers (Phase 4)
Heart Defects, Congenital (Early Phase 1)
Heart Diseases (Phase 1)
Heart Failure (Phase 4)
Heart Failure, Diastolic (Phase 4)
Heart Valve Diseases (Phase 4)
Heart Ventricles (Phase 3)
Hemodialysis, Home (Phase 2/Phase 3)
Hemolysis (Early Phase 1)
Hepatic Encephalopathy (Phase 1/Phase 2)
Hepatitis C (Phase 1)
Hernia, Diaphragmatic (Phase 4)
Hypertension (Phase 4)
Hypertension, Pulmonary (Phase 4)
Hypogonadism (Early Phase 1)
Hypoplastic Left Heart Syndrome (Phase 2)
Idiopathic Pulmonary Fibrosis (Phase 4)
Immersion (Phase 2)
Infant, Premature (Phase 2)
Infertility (Phase 4)
Infertility, Female (Phase 1/Phase 2)
Insulin Resistance (Phase 1/Phase 2)
Ischemia (Phase 2)
Ischemic Stroke (Phase 1)
Kidney Diseases (Phase 2)
Labor, Obstetric (Phase 1)
Live Birth (Phase 1)
Liver Cirrhosis (Phase 4)
Lung (Phase 1/Phase 2)
Lung Diseases (Phase 4)
Lung Diseases, Interstitial (Phase 4)
Lupus Erythematosus, Systemic (Early Phase 1)
Lymphangioma (Phase 1/Phase 2)
Lymphatic Diseases (Phase 2)
Macular Degeneration (Phase 2)
Meconium Aspiration Syndrome (Phase 4)
Meniere Disease (Phase 2)
Metabolic Syndrome (Phase 4)
Migraine with Aura (Early Phase 1)
Mitral Valve (Phase 2/Phase 3)
Muscular Diseases (Phase 4)
Muscular Dystrophy, Duchenne (Phase 2)
Myelodysplastic Syndromes (Phase 1/Phase 2)
Neoplasms (Phase 1)
Neuralgia, Postherpetic (Phase 2)
Non-alcoholic Fatty Liver Disease (Phase 2)
Obesity (Phase 4)
Ovulation (Phase 2)
Palmar Plate (Phase 1)
Pancreatic Neoplasms (Phase 1)
Parkinson Disease (Phase 4)
Peripheral Arterial Disease (Phase 3)
Persistent Fetal Circulation Syndrome (Phase 4)
Pharmacokinetics (Phase 1/Phase 2)
Post-Concussion Syndrome (Phase 2)
Pre-Eclampsia (Phase 2/Phase 3)
Premature Ejaculation (Phase 4)
Priapism (Phase 2)
Prostatic Hyperplasia (Phase 2)
Prostatic Neoplasms (Phase 4)
Prostatitis (Phase 4)
Pulmonary Arterial Hypertension (Phase 4)
Pulmonary Disease, Chronic Obstructive (Phase 4)
Pulmonary Edema (Phase 2)
Pulmonary Embolism (Phase 1)
Pulmonary Fibrosis (Phase 3)
Quality of Life (Phase 4)
Raynaud Disease (Phase 3)
Renal Dialysis (Phase 4)
Respiratory Insufficiency (Phase 2)
Retinitis Pigmentosa (Phase 2)
Risk Factors (Phase 1)
Safety (Phase 4)
Sarcoma (Phase 1)
Schizophrenia (Phase 4)
Scleroderma, Diffuse (Phase 3)
Scleroderma, Limited (Phase 3)
Scleroderma, Systemic (Phase 3)
Sclerosis (Early Phase 1)
Sexual Dysfunction, Physiological (Phase 4)
Sexual Dysfunctions, Psychological (Phase 2)
Sexual Health (Phase 2)
Smoking (Phase 1/Phase 2)
Spinal Cord Injuries (Phase 4)
Stroke (Phase 1)
Subarachnoid Hemorrhage (Phase 2)
Systole (Phase 3)
Testosterone (Phase 4)
Thalassemia (Phase 4)
Therapeutic Equivalency (Phase 1)
Thrombosis (Early Phase 1)
Traumatology (Early Phase 1)
Tricuspid Atresia (Phase 2)
Ulcer (Phase 2)
Ultrasonography (Early Phase 1)
Univentricular Heart (Phase 3)
Ureteral Diseases (Phase 4)
Urinary Bladder Neoplasms (Phase 2)
Urinary Bladder, Overactive (Phase 1)
Urinary Incontinence (Phase 2)
Urogenital Neoplasms (Phase 1)
Urolithiasis (Phase 4)
Vascular Diseases (Early Phase 1)
Vascular System Injuries (Phase 2)
Vasospasm, Intracranial (Phase 2)
Ventricular Dysfunction, Left (Phase 4)
Vitelliform Macular Dystrophy (Phase 2)
Volunteers (Phase 1)
Waldenstrom Macroglobulinemia (Phase 2)
| Trial | Phase | Start Date | Organizations | Indications |
|---|
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