abamectin Report issue

Small molecule Experimental
AACT ChEMBL MeSH PubChem

Active Ingredient History

NOW
  • Now
Abamectin is a widely used insecticide and anthelmintic. Abamectin, is a member of the Avermectin family and is a natural fermentation product of soil dwelling actinomycete Streptomyces avermitilis. Abamectin, differs from Ivermectin, the popular member of the Avermectin family, by double bond on C-22-25. Fermentation of Streptomyces avermitilis yields 8 closely related Avermectin homologues out of which B1 forms the bulk of the fermentation. The non proprietary name, abamectin, is a combination of Bla and B1b. Out of all the Avermectins, abamectin is the only one that is used both in agriculture and pharmaceuticals.   Wikipedia

Chemistry

  • SMILES: CC[C@H](C)[C@H]1O[C@@]2(C[C@@H]3C[C@@H](C\C=C(/C)\[C@@H](O[C@H]4C[C@H](OC)[C@@H](O[C@H]5C[C@H](OC)[C@@H](O)[C@H](C)O5)[C@H](C)O4)[C@@H](C)\C=C\C=C\6/CO[C@@H]7[C@H](O)C(=C[C@@H](C(=O)O3)[C@]67O)C)O2)C=C[C@@H]1C.CO[C@H]8C[C@H](O[C@H]9[C@H](C)O[C@H](C[C@@H]9OC)O[C@H]%10[C@@H](C)\C=C\C=C\%11/CO[C@@H]%12[C@H](O)C(=C[C@@H](C(=O)O[C@H]%13C[C@@H](C\C=C\%10/C)O[C@@]%14(C%13)O[C@H](C(C)C)[C@@H](C)C=C%14)[C@]%11%12O)C)O[C@@H](C)[C@@H]8O
  • InChIKey: IBSREHMXUMOFBB-JFUDTMANSA-N
  • Mol. Mass: 1732.15
  • ALogP: Missing data
  • ChEMBL Molecule:
    abamectin  
More Chemistry

Pharmacology

Alternative names

abamectin | avermectin b1 | endecto | enzec | enzek | l 676 | l-676 | l-676,863 | mk-0936 | mk 936 | mk-936 | parafoil | vertimec 18ec | vertimil | zectin

Organizations (6)

Research & Development (6)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (1)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (1)


 

Malaria (Phase 3)

Overview

  • Highest Phase: Phase 3
  • # of Trials: 1
  • # of Trial Organizations: 6

Trials by Phase

Trial Phase Start Date Organizations Indications

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