Active Ingredient History

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Bupropion, an antidepressant of the aminoketone class and a non-nicotine aid to smoking cessation, is chemically unrelated to tricyclic, tetracyclic, selective serotonin re-uptake inhibitor, or other known antidepressant agents. Compared to classical tricyclic antidepressants, Bupropion is a relatively weak inhibitor of the neuronal uptake of norepinephrine, serotonin, and dopamine. In addition, Bupropion does not inhibit monoamine oxidase. Bupropion produces dose-related central nervous system (CNS) stimulant effects in animals, as evidenced by increased locomotor activity, increased rates of responding in various schedule-controlled operant behavior tasks, and, at high doses, induction of mild stereotyped behavior. Bupropion is marketed as Wellbutrin, Zyban, and generics. Bupropion is indicated for the treatment of major depressive disorder (MDD). WELLBUTRIN, WELLBUTRIN SR, and WELLBUTRIN XL are not approved for smoking cessation treatment, but bupropion under the name ZYBAN is approved for this use.   NCATS

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Drug Pricing (per unit)

Australia

$1.3293 - $1.3294

United States

$33.5943 - $154.3287
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Note: This drug pricing data is preliminary, incomplete, and may contain errors.

amfebutamon | amfebutamone | amfebutamone hcl | aplenzin | bupropion | (+/-)-bupropion | bupropion hcl | bupropion hydrobromide | bupropion hydrochloride | bupropion hydrochloride / naltrexone hydrochloride | bw-323 | elontril | forfivo xl | tba-7371 | wellbutrin | wellbutrin 100 | wellbutrin 75 | wellbutrin sr | wellbutrin xl

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